PMID: 25743825Mar 7, 2015Paper

Clinical investigation in effect of riboflavin sodium phosphate on prevention and treatment for patients with radiotherapy related esophagitis

Asian Pacific Journal of Cancer Prevention : APJCP
Kang Shen, Xin-En Huang

Abstract

To investigate the clinical effect of riboflavin sodium phosphate on prevention of radiotherapy related esophagitis (RRE). This retrospective study involved 55 patients with middle and advanced esophageal cancer who were divided into an experimental group of 28 and a control group of 27 patients. Those in the experimental group were treated with riboflavin sodium phosphate combined with conventional symptomatic treatment during radiotherapy; while patients in control group received the latter alone. The incidence and degree of RRE were compared after radiotherapy. The incidences of RRE in experimental and control group were 53.5% and 81.4%, respectively (p<0.05); the incidence of stages III and IV RRE in the experimental group was 17.8%, while in the control group it was 44.4% (p<0.05). Riboflavin sodium phosphate could significantly prevent RRE and reduce the incidence of stage III and IV disease. These results were worthy of further confirmation by randomized controlled trials.

References

Nov 18, 2005·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·H Choy, E Vokes
Aug 15, 2008·The Oncologist·Gregory RussoMitchell Machtay
Jul 30, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Aikaterini T VasilakiDinesh Talwar
Feb 22, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Karim MakdoumiSven Crafoord
Dec 12, 2012·International Journal of Molecular Sciences·Danuta WojcieszyńskaUrszula Guzik
Oct 24, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Guang-Yu TianXin-En Huang
Oct 24, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Xin-En HuangLin Wang
Dec 19, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Ya-Dong QianXin-En Huang

❮ Previous
Next ❯

Citations

Sep 15, 2016·Thrombosis and Haemostasis·Miriam Bach, Rupert Bauersachs

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.