Clinical management of infantile cholelithiasis

Journal of Pediatric Surgery
Cerine JeantyShinjiro Hirose

Abstract

Infantile cholelithiasis is a rare disease process, and management strategies are poorly defined. We therefore examined the risk factors, complications, and management of this disease at our institution. We retrospectively reviewed infants with cholelithiasis diagnosed on ultrasound between 1997 and 2013. Details of the patient's medical history, presentation, imaging findings, laboratory values, and treatment were reviewed and analyzed. Over the 16-year period, 50 infants were evaluated for cholelithiasis. Thirty-seven (74%) had at least one risk factor for gallstone development which included total parenteral nutrition, diuretic therapy, cephalosporin antibiotic treatment, sepsis, congenital heart disease (CHD), prematurity, or a malabsorptive gastrointestinal condition. Thirteen (26%) infants were symptomatic, most commonly presenting with emesis and jaundice. Complications from gallstones included choledocholithiasis (9), cholecystitis (3), and pancreatitis (1). Nearly half (6/13) of patients with complicated cholelithiasis had CHD. Of infants presenting with complications, 9 had a cholecystectomy, most commonly via a laparoscopic approach, 2 had an ERCP for choledocholithiasis, and 2 were medically managed. In patients man...Continue Reading

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Citations

Nov 21, 2017·Radiology·Stephanie B ShamirBenjamin H Taragin
Feb 26, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Akihiko KidaAkito Sakai
Jun 21, 2016·Cardiology in the Young·Simon KarglWolfgang Pumberger
Apr 19, 2020·Journal of Pediatric Gastroenterology and Nutrition·Shankar RajeswaranSamdeep Mouli
Sep 18, 2020·Updates in Surgery·Karina Miura da Costa, Amulya Kumar Saxena
Feb 14, 2019·Journal of Ultrasound·Marco Di SerafinoGianfranco Vallone
May 28, 2020·Frontiers in Pediatrics·Gloria PelizzoValeria Calcaterra
Dec 3, 2020·Pediatrics in Review·Deborah A Goldman
Feb 23, 2021·Curēus·Mehmet Agin, Yusuf Kayar
Aug 13, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Taishi NadaKoichi Kamei

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