Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population-based study

BJOG : an International Journal of Obstetrics and Gynaecology
Linda FiaschiL J Tata

Abstract

To assess how nausea and vomiting in pregnancy (NVP) and hyperemesis gravidarum (HG) are managed and treated across primary and secondary care. Population-based pregnancy cohort. Medical records (CPRD-GOLD) from England. 417 028 pregnancies during 1998-2014. Proportions of pregnancies with recorded NVP/HG diagnoses, primary care treatment, and hospital admissions were calculated. Multinomial logistic regression was employed to estimate adjusted relative risk ratios (aRRRs) with 99% confidence intervals (CIs) for the association between NVP/HG management paths and maternal characteristics. NVP/HG diagnoses, treatments, and hospital admissions. Overall prevalence of clinically recorded NVP/HG was 9.1%: 2.1% had hospital admissions, 3.4% were treated with antiemetics in primary care only, and 3.6% had only recorded diagnoses. Hospital admissions and antiemetic prescribing increased continuously during 1998-2013 (trend P < 0.001). Younger age, deprivation, Black/Asian/mixed ethnicity, and multiple pregnancy were associated with NVP/HG generally across all levels, but associations were strongest for hospital admissions. Most comorbidities had patterns of association with NVP/HG levels. Among women with NVP/HG who had no hospital adm...Continue Reading

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Citations

Sep 14, 2019·Nature Reviews. Disease Primers·Marlena S FejzoPatrick M Mullin
Apr 17, 2020·Schizophrenia Research·Johan ReutforsGabriella Bröms
Jan 8, 2021·BMC Pregnancy and Childbirth·Roger GadsbySarah Johnson
Nov 27, 2020·Risk Management and Healthcare Policy·Huishan ZhangZhengping Liu
Jan 26, 2021·Geburtshilfe und Frauenheilkunde·Kimber W MacGibbonMarlena S Fejzo
Mar 6, 2021·Clinical Epidemiology·Marleen M H J van Gelder, Hedvig Nordeng
Nov 10, 2021·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Marco Aurelio Knippel GallettaRossana Pulcineli Vieira Francisco
Oct 9, 2021·BJGP Open·Melanie NanaCatherine Williamson

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