Clinical Manifestations and Treatment Outcomes of Eosinophilic Gastroenteritis in Children

Pediatric Gastroenterology, Hepatology & Nutrition
Jong Sub ChoiGyeong Hoon Kang

Abstract

The aim of the present study was to investigate the clinical features and outcome of eosinophilic gastroenteritis (EGE) in children. Our study enrolled 24 children who were diagnosed with EGE from 1993 to 2014 at the Department of Pediatrics, Seoul National University Children's Hospital. The patients' clinical manifestations, treatments, and outcomes were reviewed from the medical records. The mean age at diagnosis was 5.3 years. Most patients had gastrointestinal symptoms including diarrhea (54.2%) and abdominal pain (45.8%). Peripheral eosinophilia was present in 91.7% of the patients. Thirteen patients (54.2%) showed anemia, and 15 patients (62.5%) had hypoalbuminemia. EGE was classified as mucosal, subserosal, or muscular in 75.0%, 20.8%, and 4.2% of cases, respectively. Three patients showed gastroduodenal ulcers upon endoscopic analysis. A history of allergy was reported in 13 patients, including atopic dermatitis, allergic rhinitis, and asthma. Five patients (20.8%) improved with food restrictions. Among the 19 patients treated with steroids, 11 (57.9%) discontinued steroid treatment without subsequent relapse, 4 (21.1%) relapsed after ceasing steroid treatment, and 4 (21.1%) showed no response to steroids. Two patients...Continue Reading

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Citations

Apr 23, 2017·Pediatrics International : Official Journal of the Japan Pediatric Society·Mitsuaki KimuraTakaaki Meguro
Jun 1, 2018·Journal of Pediatric Gastroenterology and Nutrition·Sara Naramore, Sandeep K Gupta
Feb 21, 2019·Annals of Nutrition & Metabolism·Eleni Koutri, Alexandra Papadopoulou
May 30, 2019·Pediatric Research·Shengbo FangChunyan Li
Apr 23, 2019·The American Journal of Gastroenterology·Robert D PesekUNKNOWN Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)
Jun 25, 2019·Journal of Pediatric Gastroenterology and Nutrition·Ami MizuoTakashi Kusaka
Oct 14, 2017·Pediatric Gastroenterology, Hepatology & Nutrition·Ji Yoon KwonJee Hyun Lee
May 8, 2018·British Journal of Haematology·Gaetano BergamaschiGino R Corazza
Jun 24, 2017·Journal of Pediatric Gastroenterology and Nutrition·Swathi EluriEvan S Dellon
Jan 23, 2019·Pediatric Surgery International·Richard SolaJason D Fraser
Feb 20, 2021·Journal of Autoimmunity·Roy L J van WanrooijGerd Bouma
Jul 19, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Martina VottoAmelia Licari

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

SPSS

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