PMID: 9194111Jun 1, 1997Paper

Clinical manifestations of human immunodeficiency virus infection in Haitian children

The Pediatric Infectious Disease Journal
S S JeanP F Wright

Abstract

This study was designed to describe the characteristics of HIV-1 infection in children in Haiti and to assess its impact on morbidity and mortality. Throughout the developing world the female-to-male ratio of HIV-1 infection approaches 1:1, leading to a tremendous burden of vertically transmitted HIV-1 infection. The frequency of transmission, progression of disease and AIDS-defining clinical illnesses are not as well-described in this setting as in the industrial world. Children were identified as being HIV-1-seropositive from case findings among family members of individuals presenting for screening at the GHESKIO Centers in Port-au-Prince, Haiti. Children who were seronegative from the same population were also enrolled and both groups were followed at regular intervals. The clinical course and illnesses associated with HIV infection were documented. Rapid progression to symptomatic disease and death was seen and a battery of physical findings enabled a clinician over time to assign with high sensitivity and specificity the diagnosis of AIDS to a child. Although many findings are similar, the presentation of HIV-1 infection in Haiti differed in significant ways from observations in the industrial world. In particular signs o...Continue Reading

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Citations

May 22, 2001·AIDS Patient Care and STDs·C L BiberG G Rhoads
Feb 10, 1999·The Pediatric Infectious Disease Journal·S S JeanP F Wright
Nov 3, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Francine NoelJean W Pape
Oct 2, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·P BakakiC A Hart

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