Clinical manifestations of hypertrophic cardiomyopathy with mutations in the cardiac beta-myosin heavy chain gene or cardiac troponin T gene

Journal of Cardiac Failure
Y KogaT Imaizumi

Abstract

Introduction of molecular genetics has improved our understanding of HCM substantially, but has simultaneously raised further important questions. Studies on HCM are revealing a more complex picture than might have been expected on clinical grounds. Further extensive studies are warranted to elucidate the pathogenesis and pathophysiology of HCM, and to establish therapeutic strategies to cure or prevent the development of the disease.

Citations

Jan 6, 2005·The Japanese Journal of Physiology·K Harada, S Morimoto
Jan 3, 2001·Journal of Molecular and Cellular Cardiology·F DallozJ Robbins
Oct 5, 2017·Proceedings of the National Academy of Sciences of the United States of America·Binnu GangadharanJohn A Mercer
Mar 2, 2005·Progress in Cardiovascular Diseases·Michael S Parmacek, R John Solaro
Nov 17, 2009·Journal of Molecular and Cellular Cardiology·Ruth H WillottJames D Potter

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