Clinical manifestations of hypomagnesemia

Critical Care Medicine
M E KingstonW C Skooge

Abstract

We observed prospectively 20 consecutive patients with severe hypomagnesemia (serum Mg 0.01 to 1.2 mg/dl [0.01 to 0.5 mmol/L], mean 0.8 mg/dl [0.33 mmol/L]) before and after correction with parenteral magnesium sulfate. Only three patients, all with hypocalcemia, had tremor and muscle twitching and none showed tetany, a positive Trousseau's test, arrhythmias, or ECG abnormalities. Moreover, review of the literature on hypomagnesemia did not justify attributing these clinical symptoms to hypomagnesemia. In a follow-up study of 111 consecutive serum samples from hypocalcemic patients, 36 (32%) indicated hypomagnesemia (serum Mg no greater than 1.5 mg/dl [0.6 mmol/L]); however, hypomagnesemia had been unsuspected in all but two patients. We conclude that hypomagnesemia rarely shows specific signs or symptoms; its diagnosis depends on a high index of suspicion in patients with hypokalemia, especially after its correction, and in patients with unexplained hypocalcemia.

Citations

Aug 1, 1996·Intensive Care Medicine·R A Reinhart
Jul 1, 1993·Postgraduate Medical Journal·G P LeeseM C Browning
Jul 1, 2008·Indian Journal of Nephrology·R Satish, G Gokulnath
Jul 25, 2009·Biological Trace Element Research·Dharam P ChaudharyDevi D Bansal
Jun 4, 2002·Journal of Veterinary Internal Medicine·Jeffrey TollThomas Schermerhorn
Jan 26, 2010·Expert Opinion on Drug Safety·Pantelis A SarafidisAnastasios N Lasaridis
Aug 27, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Jacob Atsmon, Eran Dolev
Nov 1, 1994·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S M al-GhamdiR A Sutton
Jul 31, 2013·The Journal of Emergency Medicine·Ting F TsaiJohn Rutledge
Feb 1, 1989·Chest·G P Zaloga
Feb 1, 1989·Chest·B ChernowA L Warshaw
Sep 5, 2015·Journal of Critical Care·Jessica FairleyRinaldo Bellomo
Aug 12, 2009·Archives of Gerontology and Geriatrics·Zeev ArinzonYitshal Neor Berner
Oct 1, 1996·Spine·H M PlaceC W Brown
Mar 2, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ewout J HoornRobert Zietse
Sep 15, 2004·The Journal of Clinical Hypertension·Doemnic A Sica
May 1, 1990·Progress in Cardiovascular Diseases·P K Keller, R S Aronson
Apr 1, 1988·Disease-a-month : DM·R J Elin
Nov 1, 1992·The Journal of Emergency Medicine·E L Tso, R A Barish
Nov 9, 2012·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Rui-Yun LiangYing Lin
Mar 11, 1991·Journal of the American College of Cardiology·R A ReinhartR G Haas
Apr 23, 1999·Cancer Treatment Reviews·H Lajer, G Daugaard
Feb 20, 1999·Veterinary Surgery : VS·J D Wooldridge, C R Gregory
Nov 25, 2005·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Michael D KraftGordon S Sacks
Sep 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·J Massé
Mar 22, 2006·Acta Anaesthesiologica Scandinavica·A PapaioannouH Askitopoulou
Jul 8, 2009·Dermatologic Therapy·Damon McClainGary Goldenberg
Aug 1, 1994·Annals of the Rheumatic Diseases·I F IslimR D Watson
Nov 9, 2000·American Journal of Clinical Pathology·H J HuijgenG T Sanders
Jul 31, 2003·The Journal of Nutrition·Hélène MartinAlain Berthelot
Jun 29, 2018·Internal and Emergency Medicine·Geoffrey CheminetJean-Benoît Arlet
Aug 1, 1996·Intensive Care Medicine·C GuérinG Fournier
Jul 1, 1987·Drug Intelligence & Clinical Pharmacy·J M Mirtallo, T Oh
Nov 12, 2020·American Journal of Physiology. Endocrinology and Metabolism·Theo A T G van Kempen, Elisabeth Deixler
Aug 27, 2018·Journal of Cardiothoracic and Vascular Anesthesia·Matteo Parotto, George Djaiani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.