Clinical narrative: autoimmune hepatitis

The American Journal of Gastroenterology
Paul A Schmeltzer, Mark W Russo

Abstract

Autoimmune hepatitis (AIH) is an inflammatory liver disease that is characterized by circulating autoantibodies, hypergammaglobulinemia, and a lymphoplasmocytic infiltration with interface hepatitis on liver biopsy. Treatment with corticosteroids and other immunosuppressive agents is effective and early diagnosis can result in near-normal life expectancy. Untreated patients, however, can progress to cirrhosis and liver failure. The clinical presentation is heterogeneous and may pose diagnostic and therapeutic dilemmas. This case-based review will address the diagnosis and management of this disease, in addition to difficult but commonly encountered clinical scenarios.

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Citations

Apr 12, 2019·Alimentary Pharmacology & Therapeutics·Amanda J NicollUNKNOWN ALA Clinical Research Network, Gastroenterological Society of Australia
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Jun 3, 2019·European Journal of Gastroenterology & Hepatology·Zhen-Jun YuZe-Bao He
Sep 11, 2019·Chinese Journal of Integrative Medicine·Yu-Tong Liu, Wen-Liang Lv
Jan 5, 2019·Hepatology International·Naoshi Nishida, Masatoshi Kudo
Aug 28, 2021·Diagnostics·Weronika DomereckaTeresa Małecka-Massalska

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