Clinical neurologic indices of toxicity in animals

Environmental Health Perspectives
J L O'Donoghue

Abstract

The fundamental structures and functions of the nervous systems of animals and humans are conserved in many ways across species. These similarities provide a basis for developing common neurologic examinations for a number of species of animals and also provide a basis for developing risk assessments across species for neurologic end points. The neurologic examination requires no expensive equipment and can be conducted in the field or wherever impaired animals are identified. The proper conduct of neurologic examinations in animals assumes that the examiner has a fundamental understanding of the normal structure and function of the nervous system as well as knowledge about the spontaneous disease background of the species being studied.

References

Nov 1, 1969·Experimental Neurology·G V GoddardC K Leech
Oct 29, 1971·Science·J F MarshallP Teitelbaum
May 1, 1982·Journal of Toxicology and Environmental Health·S C Gad

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Citations

Apr 1, 1996·Environmental Health Perspectives·B KuligD Peakall
Oct 7, 1998·Neurotoxicology and Teratology·W Briner, S Peterson
Oct 6, 1997·Neurotoxicology and Teratology·J F RossG J Carr
Nov 16, 2010·Toxicologic Pathology·Virginia C Moser
May 1, 2001·Current Protocols in Toxicology·V C Moser

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