PMID: 20654059Jul 27, 2010Paper

Clinical observation of therapeutic efficacy and study of conjunctival impression cytology after pterygium surgery

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Jun-ru LiuWei Wang

Abstract

To compare the pathologic changes, the recurrence rate and the ocular surface damage after 4 different types of pterygium surgical procedures. It is a prospective study. From Mar. 2006 to Mar. 2008, 84 patients (93 eyes) from Shi Jia-zhuang Center Hospital were selected and separated into 4 groups as follows, simple excision group, 24 patients (27 eyes); excision with conjunctival allograft group, 21 patients (22 eyes) excision with autologous limbus stem cell transplantation group, 18 patients (20 eyes) and excision with mitomycin (MMC) group, 21 patients (24 eyes). Slit lamp microscope examination and impression cytology were performed 1 day before the surgery and repeated 30 and 90 days after the surgery. Multivariate analysis of variance was used to analyze these data with statistical software SPSS 11.0. P value less than 0.05 was considered statistically significant. Before the surgery, slight conjunctival epithelium keratinization, mild acantholysis and decrease in goblet cells density were identified in all patients (248.8 +/- 97.3, 256.2 +/- 75.1, 236.1 +/- 87.9, 245.1 +/- 81.0; F = 0.029, P = 0.993). All of these changes decreased 1 month after the surgery. MMC group showed more goblet cells than the other 3 groups, bu...Continue Reading

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