PMID: 9548225Apr 21, 1998Paper

Clinical observations of juvenile myoclonic epilepsy in 131 patients: a study in South India

Seizure : the Journal of the British Epilepsy Association
J M MurthyA K Meena

Abstract

We studied clinical features of 131 patients with juvenile myoclonic epilepsy (JME). The prevalence was 7.7% among the epileptic patients registered. The mean age at onset was 13.37+/-4.93 years and the diagnosis was established at a mean age of 19.53+/-7.85 years. Absence seizures were reported by 27 (20.6%) patients, myoclonic jerks by 131 (100%) and generalized tonic-clonic seizures (GTCS) by 111 (84.7%). The triad of absence seizures, myoclonic jerks and GTCS was noted in 23 (17.5%) patients, 88 (67.2%) had myoclonic jerks and GTCS, 4 (3%) had absence seizures and myoclonic jerks and 16 (12.2%) had only myoclonic jerks. Early onset absences were seen in 21 (16%) patients and the onset was late in 6 (4.6%). Absences antedated other types of seizures in all the patients. Myoclonic jerks were predominantly unilateral or had unilateral onset in 22 (16.8%). In 17 (13%) patients GTCS antedated myoclonic jerks. Myoclonic jerks had characteristic circadian distribution in 112 (85.5%) patients. On awakening GTCS occurred in 87 (78.4%) patients and in 4 (3.6%) patients they were purely nocturnal. Sleep deprivation was the most important precipitating factor (54.2%). Initial electroencephalogram (EEG) showed classical generalized spik...Continue Reading

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Citations

Sep 12, 2003·Seizure : the Journal of the British Epilepsy Association·J VijaiK Radhakrishnan
Feb 1, 2003·Epilepsia·J M K Murthy
Mar 15, 2006·Epilepsia·Luiz Eduardo BettingFernando Cendes
May 21, 2009·Epilepsia·Mirian Salvadori Bittar GuaranhaElza Márcia Targas Yacubian
Jan 26, 2011·Annals of Indian Academy of Neurology·Sridharan Ramaratnam, P Satishchandra
Feb 15, 2016·Seizure : the Journal of the British Epilepsy Association·Dilek AtakliHüseyin Sari
Dec 30, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Giorgi JaparidzeSándor Beniczky
May 6, 2014·Seizure : the Journal of the British Epilepsy Association·Sita JayalakshmiSurath Mohandas
Aug 8, 2001·Seizure : the Journal of the British Epilepsy Association·A K DhanukaD Maheshwari
Feb 24, 2006·Seizure : the Journal of the British Epilepsy Association·S Sita JayalakshmiRupam Borgohain
Jun 16, 2005·Seizure : the Journal of the British Epilepsy Association·Patrícia da Silva SousaElza Márcia T Yacubian
Jan 16, 2007·Seizure : the Journal of the British Epilepsy Association·A ChakravartyD Roy
Mar 1, 2012·Epilepsy & Behavior : E&B·Pramod KrishnanParthasarathy Satishchandra
Sep 19, 2002·Seizure : the Journal of the British Epilepsy Association·M M Mehndiratta, P Aggarwal
Jun 14, 2013·Epilepsy & Behavior : E&B·Anna SerafiniPhilippe Gelisse
Aug 2, 2005·Arquivos de neuro-psiquiatria·Nise Alessandra de Carvalho SousaElza Márcia Targas Yacubian
Jul 10, 2001·Acta Neurologica Scandinavica·A PanagariyaV Sardana
Apr 26, 2003·Acta Neurologica Scandinavica·S JainA Narula

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