Clinical outcome after acute coronary syndrome in Japanese patients: an observational cohort study

Journal of cardiology
Michinari NakamuraTadanori Aizawa

Abstract

Mortality and morbidity after acute coronary syndrome (ACS) in Japan appear to be different from those in Western countries due to different social healthcare systems, races, geographical locations, and interventional procedures, although data are limited in Japan. With a hospital-based cohort study comprising all the new patients who had visited our hospital between 2004 and 2007 (n=6562), we identified all-cause mortality, the composite endpoint of cardiac death, non-fatal myocardial infarction (MI), or target vessel revascularization and the predictors. Of the total, 293 patients were included with a discharge diagnosis of ACS (median follow-up of 24.5 months). Non-ST elevation-ACS (NSTE-ACS) (unstable angina and non-ST elevation MI) and ST elevation MI (STEMI) were observed in 165 (56.3%) and 128 (43.7%) patients, respectively. Percutaneous coronary intervention or coronary artery bypass graft surgery was performed in 72.7% and 14.5% of NSTE-ACS patients, respectively and in 82.8% and 10.2% of STEMI patients. The use of aspirin, ticlopidine, and beta-blockers for NSTE-ACS patients were 93.3%, 66.9%, and 38.0%, respectively, with corresponding rates of 96.0%, 75.4%, and 57.1% for STEMI patients. All-cause mortality rates in ...Continue Reading

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Citations

Aug 13, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Michinari NakamuraUNKNOWN Shinken Database Study Group
Oct 18, 2015·International Journal of Cardiology·Mark Y ChanYoung-Hoon Jeong
Jan 24, 2012·Journal of cardiology·Hamidreza RoohafzaMasoumeh Sadeghi
Apr 10, 2013·The Journal of International Medical Research·Katsumi Miyauchi, Kausik Ray
Mar 5, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Tetsuya MatobaHiroyuki Tsutsui

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