Clinical Outcome and Comparison of Three Different Left Ventricular Assist Devices in a High-Risk Cohort

Artificial Organs
Konstantin ZhigalovAlexander Weymann

Abstract

We present a comparison between three left ventricular assist devices (LVADs): HeartWare (HVAD) (HeartWare International Inc., Framingham, MA, USA), HeartMate II (HMII) and HeartMate III (HMIII) (Thoratec Corp., Pleasanton, CA, USA). To our knowledge, no study to date has aimed at placing these three devices in juxtaposition. Between June 2007 and June 2017, 108 consecutive patients received HMII, n = 77 (71.3%), HVAD, n = 14 (13%), or HM III, n = 17 (15.7%), for end-stage heart failure. Mean age was 63.8 ± 11.2 years (range 24-84 years), with median INTERMACS profile of 3. Preoperatively, 26 patients (24.1%) were ventilated, 17 patients (15.7%) had an intraaortic balloon pump, and 27 patients (25%) were on extracorporeal life support. Overall survival at 30 days was 70.4%, at 1 year 51.9%, and at 5 years 38% with no significant difference in survival between HMII, HVAD, and HMIII. Median cardiopulmonary bypass time was 113 min (range 50-371 min). Two patients received a minimally-invasive procedure. Most common adverse events were revision for bleeding (42.6%), tracheotomy (33.3%), acute kidney failure with new-onset dialysis (25%), sepsis (17.6%), and gastrointestinal bleeding (10.2%). The average duration of follow-up was 1....Continue Reading

References

Nov 17, 2011·Circulation. Heart Failure·Jorge SuarezJoseph G Rogers
Jan 9, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Anton SabashnikovAndré R Simon
Jan 29, 2016·Artificial Organs·Paul S Malchesky
Sep 14, 2016·Journal of Thoracic Disease·Anatol PrinzingBernhard Voss
Jun 2, 2017·Annals of Biomedical Engineering·Marianne Schmid DanersVolkmar Falk
Jun 10, 2017·Journal of the American College of Cardiology·Sean P PinneyMandeep R Mehra
Sep 26, 2017·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·James K KirklinDavid C Naftel

❮ Previous
Next ❯

Citations

Jan 27, 2019·Artificial Organs·Paul S Malchesky
Mar 29, 2019·The International Journal of Artificial Organs·Konstantin ZhigalovAlexander Weymann
Aug 24, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Elena CavarrettaGiacomo Frati
Apr 22, 2020·The International Journal of Artificial Organs·Peng FangShunzhou Yu
Sep 12, 2018·International Anesthesiology Clinics·Vidya K Rao, Albert Tsai
Oct 30, 2020·Medicina·Konstantin ZhigalovAlexander Weymann
Jan 13, 2021·Artificial Organs·Vikas KannojiyaPrasanta Kumar Das
Aug 28, 2020·Heart, Lung & Circulation·Sinan Sabit KocabeyogluMustafa Pac

❮ Previous
Next ❯

Related Concepts

Related Feeds

Artificial Heart & Ventricular Assist Devices

Total artificial hearts (TAH) and ventricular assist devices (VADs) provide cardiac support for patients with end-stage heart disease and have significantly improved the survival of these patients. Discover the latest research on Artificial Heart and Ventricular Assist Devices here.

Related Papers

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Ingvild BirschmannMartin Strüber
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Ruth Pulikottil-JacobAileen Clarke
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Sajad ShehabChristopher S Hayward
© 2022 Meta ULC. All rights reserved