PMID: 15373989Sep 18, 2004Paper

Clinical outcome and reversibility of systolic dysfunction in patients with dilated cardiomyopathy due to hypertension and chronic heart failure

Revista española de cardiología
Manuel Anguita SánchezFederico Vallés Belsué

Abstract

There is little information on the clinical and functional course of patients with heart failure secondary to dilated cardiomyopathy due to hypertension. The objectives of our study were to assess the clinical and functional course of these patients, and to identify possible predictors of prognosis. We evaluated a series of 49 patients with this condition diagnosed in our hospital from 1994 to 2003. Mean age was 63(11) years, and 40% were women. Left ventricular ejection fraction was 30.1(4.8)%. Follow-up was 45(23) months (median, 41 months). Four-year survival was 0.84, the 4-year rate of hospitalization due to heart failure was 0.12, and likelihood of readmission-free survival was 0.80 at 4 years. Left ventricular ejection fraction increased from 30.1(4.8)% to 57.6(13.5)% (P< .001). An unfavorable clinical and functional outcome at 4 years (death, readmission for heart failure or persistence of dilated cardiomyopathy) was recorded in only in 40% of the patients. Multivariate analysis with the Cox model showed appropriate control of blood pressure to be the only independent predictor of a favorable clinical outcome (absence of death or readmission for heart failure) (hazard ratio = 4.58; 95% CI, 1.32-9.83; P=.032). The course...Continue Reading

References

Oct 22, 1979·The American Journal of Cardiology·B E Strauer
Jun 1, 1991·American Heart Journal·J R TeerlinkM A Pfeffer
Aug 1, 1994·British Heart Journal·W B KannelT Thom
Sep 15, 1993·The American Journal of Cardiology·T H LeeJ A Walden
Feb 13, 2001·European Heart Journal·K F FoxG C Sutton

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Citations

Dec 19, 2008·The Journal of Clinical Hypertension·Vivencio BarriosAlberto Calderón

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