Clinical outcome in patients from a single region who were dependent on parenteral nutrition for 28 days or more

Archives of Disease in Childhood
J KöglmeierJohn W L Puntis

Abstract

The frequency and outcome of intestinal failure (IF) in children are not well defined in the UK. Long-term parenteral nutrition (PN) is an effective intervention, with intestine transplantation offering the possibility of survival should life-threatening complications arise in those with long-term dependency. The ideal model for service provision is a subject of debate. We aimed to identify all new cases of IF (defined as PN dependency > or =28 days) in West Yorkshire over a two-year period to determine the rate of serious complications, establish the outcome after two years and clarify the role of specialist referral. Pharmacists in all the West Yorkshire paediatric units were contacted to establish the number of children with IF during 2001-2002. Underlying diagnosis, complications and outcome at two years were obtained by case-note review for 93 of the 96 children identified. IF patients were exclusively managed in one or other of the three large teaching hospitals. At the two-year follow-up, six (6.4%) children had died (one while listed for a small bowel transplantation), but 85 (91%) had established full enteral feeding and were well. Two remained PN dependent and were assessed in the supra-regional intestinal transplanta...Continue Reading

Citations

Oct 16, 2013·Early Human Development·A Batra, R M Beattie
Feb 14, 2012·Journal of Pediatric Surgery·Mark BishayAgostino Pierro
Nov 3, 2010·Journal of the American Dietetic Association·Catherine J KleinLouis Scavo
Dec 6, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Andrew R BarclayUNKNOWN BIFS collaborators
Apr 2, 2009·Paediatric Anaesthesia·Urban Flaring, Yigael Finkel
Mar 11, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·S V BeathJ W L Puntis
Nov 1, 2012·JPEN. Journal of Parenteral and Enteral Nutrition·Joseph I BoullataJay M Mirtallo
Jan 31, 2015·Journal of Pediatric Gastroenterology and Nutrition·Jonas TengBjörn Fischler
Oct 23, 2020·Archives of Disease in Childhood·Rachel Pybus, John W Puntis
Feb 12, 2020·Journal of Pediatric Nursing·Maria Samuelsson, Anne Wennick
Aug 28, 2021·Nutrients·José Vicente N SpolidoroNatascha Silva Sandy
Mar 6, 2009·Current Opinion in Supportive and Palliative Care

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.