Clinical outcome of EMR of sporadic, nonampullary, duodenal adenomas: a 10-year retrospective

Gastrointestinal Endoscopy
Yutaka Tomizawa, Gregory G Ginsberg

Abstract

Sporadic non-ampullary duodenal adenomas (SNADAs), although uncommon, pose clinical challenges. Because SNADAs have malignant potential, endoscopic or surgical resection is generally recommended. EMR is increasingly used for resection of SNADAs, but large-scale data on natural history after EMR are scarce. In this study, we aimed to evaluate the clinical outcome of EMR for SNADAs and the natural history after EMR from a large, single-operator experience with dedicated follow-up. We performed a retrospective review of patients with SNADAs who were referred for endoscopic therapy from May 2007 to May 2016. Patient demographics, lesion characteristics, and procedural technical data were collected. The outcomes studied were complete endoscopic resection, major adverse events, and recurrence. A total of 162 patients were referred for endoscopic therapy, and 142 (88%) (median age 67 years, interquartile range [IQR] 57-73 years, 42% male) underwent a total of 166 EMRs with the use of a submucosal injection and thermal snare resection technique. In per-patient analysis, the median size of SNADAs was 20 mm (IQR 15-30) in diameter. Complete mucosal resection was achieved in 130 of 142 patients (92%). Local or residual recurrences were ob...Continue Reading

Citations

Aug 8, 2018·Endoscopy International Open·Enrique Pérez-Cuadrado-RoblesPierre H Deprez
Jan 31, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yosuke ToyaTakayuki Matsumoto
Feb 23, 2019·United European Gastroenterology Journal·Sharmila SubramaniamPradeep Bhandari
Feb 21, 2019·World Journal of Gastroenterology : WJG·Yuko HaraHisao Tajiri
Jun 22, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Eisuke IwasakiTakanori Kanai
Oct 2, 2020·Journal of Gastroenterology and Hepatology·Masao YoshidaUNKNOWN Japan Duodenal Cancer Guideline Committee
Jan 5, 2021·World Journal of Clinical Cases·Xiao-Yu LiKun-Peng Zhang
Mar 19, 2021·Scandinavian Journal of Gastroenterology·Yi Fang, Xiaoyun Ding
Apr 28, 2021·Gastrointestinal Endoscopy·Ross C D Buerlein, Andrew Y Wang
Apr 27, 2021·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Hyo-Joon Yang
Jul 5, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Yasushi YamasakiUNKNOWN D-UEMR Study Group

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