PMID: 25757349Mar 12, 2015Paper

Clinical outcomes after combined therapy with dutasteride in patients with unsuccessful trial without catheter after treatment with an alpha1-adrenergic receptor blocker monotherapy for acute urinary retention caused by prostatic hyperplasia

Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
Masahiko InaharaYukio Naya

Abstract

The outcome of trial of voiding without catheter in patients treated combination therapy with dutasteride and alpha1-adrenergic receptor blocker for acute urinary retention caused by benign prostatic hyperplasia was not reported. We evaluated the clinical efficacy of combination therapy with dutasteride in patients with unsuccessful trial without catheter after treatment with an alpha1-adrenergic receptor blocker monotherapy for acute urinary retention caused by benign prostatic hyperplasia. Patients with acute urinary retention due to prostatic hyperplasia were catheterized and treated alpha1-adrenergic receptor blocker monotherapy. After two weeks later, patients were put on trial without catheter. 52 patients who were unsuccessful trial without catheter administered combination therapy with dutasteride and alpha1-adrenergic receptor blocker. We use criteria that voiding urine volume over 100 ml and post-void residual urine volume below 100 ml in deciding whether catheter should be removed. 33 (63.5%) men did not require re-catheterization within 7 months after combination therapy. The successful rate of Performance Status (PS) 0-1 group was significantly superior to that of PS 2-4 group. PS 0-1 men catheterized for AUR can v...Continue Reading

References

Dec 4, 2009·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Madhu S AgrawalRicha Jaiman
Jul 11, 2012·International Journal of Urology : Official Journal of the Japanese Urological Association·Byung-Ha ChungUNKNOWN CombAT Study Group

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