Clinical outcomes after magnetic resonance angiography (MRA) versus computed tomographic angiography (CTA) for pulmonary embolism evaluation

Emergency Radiology
Michael D RepplingerMark L Schiebler

Abstract

To compare patient outcomes following magnetic resonance angiography (MRA) versus computed tomographic angiography (CTA) ordered for suspected pulmonary embolism (PE). In this IRB-approved, single-center, retrospective, case-control study, we reviewed the medical records of all patients evaluated for PE with MRA during a 5-year period along with age- and sex-matched controls evaluated with CTA. Only the first instance of PE evaluation during the study period was included. After application of our exclusion criteria to both study arms, the analysis included 1173 subjects. The primary endpoint was major adverse PE-related event (MAPE), which we defined as major bleeding, venous thromboembolism, or death during the 6 months following the index imaging test (MRA or CTA), obtained through medical record review. Logistic regression, chi-square test for independence, and Fisher's exact test were used with a p < 0.05 threshold. The overall 6-month MAPE rate following MRA (5.4%) was lower than following CTA (13.6%, p < 0.01). Amongst outpatients, the MAPE rate was lower for MRA (3.7%) than for CTA (8.0%, p = 0.01). Accounting for age, sex, referral source, BMI, and Wells' score, patients were less likely to suffer MAPE than those who un...Continue Reading

References

May 15, 1997·The New England Journal of Medicine·J F MeaneyM R Prince
Apr 22, 2005·Journal of Thrombosis and Haemostasis : JTH·S SchulmanUNKNOWN Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on T
Jan 13, 2006·JAMA : the Journal of the American Medical Association·Arne van BelleUNKNOWN Christopher Study Investigators
Feb 8, 2006·Annals of Internal Medicine·Grégoire Le GalArnaud Perrier
Dec 23, 2006·Radiology·Paul D SteinUNKNOWN PIOPED II Investigators
Nov 30, 2007·The New England Journal of Medicine·David J Brenner, Eric J Hall
Jan 30, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Anja C S BrauRoland Bammer
Mar 7, 2008·The New England Journal of Medicine·Victor F Tapson
Jun 30, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Pamela S DouglasJames Udelson
Apr 7, 2010·Annals of Internal Medicine·Paul D SteinUNKNOWN PIOPED III (Prospective Investigation of Pulmonary Embolism Diagnosis III) Investigators
May 11, 2011·Archives of Internal Medicine·Renda Soylemez WienerSteven Woloshin
Feb 11, 2012·Journal of Thrombosis and Haemostasis : JTH·M P RevelG Chatellier
Jun 8, 2012·Journal of Thrombosis and Haemostasis : JTH·M CarrierG Le Gal
Apr 5, 2013·Journal of Magnetic Resonance Imaging : JMRI·Mark L SchieblerScott B Reeder

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Citations

Aug 8, 2018·Current Treatment Options in Cardiovascular Medicine·Leonid Roshkovan, Harold Litt
Jun 23, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gesine KnoblochScott K Nagle
Aug 17, 2020·The British Journal of Radiology·Mark L SchieblerEdwin van Beek

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