Clinical Outcomes After Percutaneous Patent Ductus Arteriosus Closure in Adults.

The Canadian Journal of Cardiology
William M WilsonEric M Horlick

Abstract

There is little published data regarding percutaneous patent ductus arteriosus (PDA) closure in adults. We aim to describe the outcomes of adult patients undergoing PDA closure at a single tertiary referral centre. All adults who underwent device PDA closure at our centre from 2001 to 2017 were identified and enrolled in the study. Available clinical data and imaging data were reviewed. At total of 141 patients were identified, with a mean age of 43 ± 15 years. Left ventricular dilation was present in 27% and pulmonary hypertension in 36% of the patients. Most ducts (74%) were of type A morphology. Mean ductal diameter at the pulmonary artery end was 4.1 ± 1.9 mm and mean length was 10.0 ± 4.7 mm. Wire passage from the pulmonary artery was achieved in 79%. Procedural success rate was 100%, and an Amplatzer duct occluder was deployed in all successful cases (ADO1 device in 97%). There was a small residual shunt in 6% at the time of closure, and only 2 patients had a residual leak on echocardiography at a median 3 months' follow-up. No major complications occurred. Transcatheter PDA closure with the use of an Amplatzer duct occluder is very effective in adults across all duct morphologies and associated with a very low complicati...Continue Reading

Citations

Mar 17, 2020·The Canadian Journal of Cardiology·Michael L O'ByrneMatthew J Gillespie
May 15, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Jimmy WindsorHarish Ramakrishna
Aug 18, 2021·Current Problems in Cardiology·Zahra KhajaliZahra Hosseini

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