Abstract
Persons with haemophilia and other inherited bleeding disorders are prone to disabling joint arthropathy frequently requiring arthroplasty for end-stage joint disease. Higher complication rates and more modest post-operative functional outcomes have previously been described. To evaluate the clinical outcomes and patient satisfaction of persons with inherited bleeding disorders (predominantly haemophilia) undergoing total hip and knee replacement. Retrospective, single-centre cohort study with longitudinal assessment of patients with inherited bleeding disorders who underwent total hip and knee replacement over a 20-year period. Eligible patients were clinically assessed with Harris Hip Score (HHS), Knee Society Score (KSS), pain visual analogue scale (VAS) and a patient satisfaction questionnaire. Thirty-one patients (48 joints) met the inclusion criteria. Mean age at surgery was 49.3 years (SD: 13.1, range 21-75 years) with a mean follow-up of 9.33 years (1.7-19.3). The majority (26/31) of patients had haemophilia A, predominantly severe haemophilia A (22/26). Reported pain levels were low, and patient satisfaction was high. Joint-specific outcome scores were "good" to "excellent" in 67% of total hip replacement patients and ...Continue Reading
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Apr 2, 2019·Expert Review of Hematology·E Carlos Rodriguez-Merchan
Oct 9, 2019·Expert Review of Hematology·Emerito-Carlos Rodriguez-Merchan
Jul 29, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Zeng LiXisheng Weng
Dec 29, 2018·British Journal of Haematology·Susan Shapiro, Mike Makris
Sep 30, 2021·Journal of Orthopaedic Surgery·Kunal MohanNiall Hogan
Dec 3, 2021·Foot & Ankle International·Alisa MalyavkoBenjamin E Stein
Jan 22, 2022·Journal of Orthopaedic Trauma·Aria D DarbandiFaran Bokhari