Clinical outcomes and therapeutic strategy in patients with acute myocardial infarction according to renal function: data from the Korean Acute Myocardial Infarction Registry

Circulation Journal : Official Journal of the Japanese Circulation Society
Sang-Hee LeeKorean Acute Myocardial Infarction Registry Investigators

Abstract

The aim of the present study was to evaluate the relationship between clinical outcomes after acute myocardial infarction (MI) and renal function by glomerular filtration rate (GFR) in patients with normal or mildly elevated serum creatinine concentrations. As part of the Korean Acute Myocardial Infarction Registry (KAMIR), 6,834 acute MI patients with a serum creatinine concentration of <or=2.0 mg/dl were enrolled from November 2005 to December 2006. The renal function was stratified arbitrary to 5 groups: (1) normal function, >90.0; (2) preserved function, 75.0-89.9; (3) mild dysfunction, 60.0-74.9; (4) moderate dysfunction, 45.0-59.9; (5) severe dysfunction, <45 ml.min(-1). 1.73 m(-2). Clinical characteristics, mortality and adverse events were analyzed among each group. Although reperfusion and medical therapies were underused, the rates of mortality and adverse events were increased with declining renal function. After adjustment with confounders, severe and moderate renal dysfunctions were important risk predictors of in-hospital mortality, long-term mortality and adverse events. The spectrum of renal function, when it was presented by GFR, is broad and is an important risk predictor for adverse outcomes after acute MI, e...Continue Reading

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Citations

Mar 28, 2017·International Journal of Cardiology·Jin Sug KimKyung Hwan Jeong
Nov 8, 2014·The Korean Journal of Internal Medicine·Hyun Kuk KimYoung Jo Kim
Feb 5, 2021·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Yong HuoHéctor Bueno
Jun 30, 2011·The American Journal of Cardiology·Daisuke HachinoheUNKNOWN Other Korea Acute Myocardial Infarction Registry Investigators

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