Clinical outcomes in adult athletes with hypertrophic cardiomyopathy: a 7-year follow-up study

British Journal of Sports Medicine
Antonio PellicciaCamillo Autore

Abstract

Current guidelines recommend precautionary disqualification from competitive sports in patients with hypertrophic cardiomyopathy (HCM). We assessed the incidence of cardiovascular events in a cohort of patients with HCM engaged in long-term exercise programmes and competitive sport. We reviewed data on 88 consecutive athletes diagnosed with HCM, from 1997 to 2017; 92% male, 98% Caucasian, median age 31 (IQR: 19-44) years. All participated in regular exercise programmes and competitive sport at study entry.We performed follow-up evaluation after 7±5 (1-21) years. 61 (69%) of the athletes had substantially reduced or stopped exercise and sport (ie, HCM-detrained), and 27 had continued with regular training and sport competitions (HCM-trained). At baseline evaluation, both groups were similar for age, gender balance, symptoms, ECG abnormalities, extent of left ventricular hypertrophy, arrhythmias and risk profile for sudden cardiac death/arrest. During the follow-up period, two participants suffered sudden cardiac arrest or death (0.3% per year) both outside of sport participation. In addition, 19 (22%) reported symptoms (syncope in 3, palpitations in 10, chest pain in 4 and dyspnoea in 2). The Kaplan-Meier analyses of freedom fro...Continue Reading

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Citations

Jan 22, 2021·British Journal of Sports Medicine·Jonathan A DreznerSanjay Sharma
Mar 29, 2021·Revista Española De Cardiología·UNKNOWN SEC Working Group for the 2020 ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular DiseaseUNKNOWN SEC Guidelines Committee
Mar 27, 2021·American Journal of Physiology. Heart and Circulatory Physiology·Adaya Weissler SnirPaul Dorian
Jun 1, 2021·Current Treatment Options in Cardiovascular Medicine·Bradley S LanderElizabeth H Dineen

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