Clinical Outcomes of a Customized Mitral Valve Plasty for Functional Mitral Regurgitation with a Low Ejection Fraction and Implications for Preoperative Right Ventricular Function.

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
Koji FurukawaKunihide Nakamura

Abstract

To evaluate clinical outcomes of customized mitral valve plasty (MVP) for the treatment of functional mitral regurgitation (FMR) with a low ejection fraction (EF) and to determine which preoperative factors affected the clinical outcome. MVP was adjusted according to the degree of left ventricle (LV) remodeling. We performed mitral annuloplasty (MAP) alone in 14 patients and added subvalvular procedures (SVPs) in 22 patients at a high risk of recurrent MR. During follow-up, reverse LV remodeling was obtained and the 3-year and 5-year non-recurrence rates of MR grade ≥2 were 94% and 89%, respectively. Two patients died during their hospital stay, and four more patients died of cardiac causes during follow-up. The 3-year and 5-year rates of freedom from cardiac-related mortality were 86% and 81%, respectively; no significant difference was observed between the two treatment groups. Right ventricular fractional area change (RVFAC) was a significant predictor of cardiac mortality. Patients with an RVFAC of <26% had significantly poorer cardiac-related mortality (71% at 3 years) than those with an RVFAC of ≥26% (95% at 3 years). Customized MVP provided durable mitral competence and reverse LV remodeling. Preoperative RV function was...Continue Reading

References

Apr 1, 1995·Journal of the American College of Cardiology·T G Di SalvoG W Dec
Oct 13, 1998·Journal of the American College of Cardiology·P de GrooteJ M Lablanche
Jun 28, 2001·The Annals of Thoracic Surgery·R U NairL B Tan
Aug 14, 2002·The Annals of Thoracic Surgery·Irving L KronJeffrey T Cope
Mar 29, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Tadashi IsomuraUNKNOWN RESTORE Group
May 30, 2007·The Journal of Thoracic and Cardiovascular Surgery·Michael A BorgerTirone E David
Sep 25, 2007·European Heart Journal·Michele Di MauroSabina Gallina
Apr 17, 2013·Heart, Lung & Circulation·Konstantin SchwarzMichael P Frenneaux
Nov 20, 2013·The New England Journal of Medicine·Michael A AckerUNKNOWN CTSN
Apr 24, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Andrea GarattiLorenzo Menicanti
Nov 19, 2014·The New England Journal of Medicine·Peter K SmithUNKNOWN Cardiothoracic Surgical Trials Network Investigators
Apr 7, 2015·The Annals of Thoracic Surgery·Christos G MihosOrlando Santana
Nov 10, 2015·The New England Journal of Medicine·Daniel GoldsteinUNKNOWN CTSN
May 21, 2016·Journal of the American College of Cardiology·Francesco NappiMassimo Chello
Sep 27, 2016·The Annals of Thoracic Surgery·Vincent ChanThierry G Mesana
Jun 24, 2017·Interactive Cardiovascular and Thoracic Surgery·Leonidas V AthanasopoulosThanos Athanasiou

❮ Previous
Next ❯

Citations

Oct 6, 2020·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Francesco Nappi
Jul 15, 2021·BioMed Research International·Francesco NappiMassimo Chello

❮ Previous
Next ❯

Software Mentioned

MitraClip

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.

Acute viral rhinopharyngitis

Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.