Clinical outcomes of botulinum toxin type A injections in the management of primary bruxism in adults: A systematic review.

The Journal of Prosthetic Dentistry
Luiza Abreu SendraEliane Porto Barboza

Abstract

Botulinum toxin has been used for various therapeutic and esthetic purposes for nearly 4 decades and has shown positive outcomes in patients with bruxism. However, the effectiveness of botulinum toxin injections as an alternative to traditional therapies in the management of primary bruxism is still unclear. The purpose of this systematic review was to analyze the clinical outcomes of the use of botulinum toxin type A injections in the management of primary bruxism in adults. Databases such as PubMed, Web of Science, Scopus, LILIACS, Cochrane Library, and Open Grey Literature were searched without language or date restrictions until October 6, 2019. Using Mendeley Desktop software to organize the references, 2 independent researchers selected the published clinical studies (Study type) on the improvement of symptoms (Outcome) in human adults with primary bruxism (Participants/Population) who received botulinum toxin type A injections (Intervention), placebo injections, saline injections, no injections, or other treatments (Comparator(s)/Control) for the management of bruxism. A total of 601 references were initially obtained from the 6 databases. Six randomized clinical trials and 4 case series were selected and critically appr...Continue Reading

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Citations

Jan 13, 2021·Toxins·Charenya Anandan, Joseph Jankovic

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