Clinical outcomes of end-flexible-rigidscopic transoral surgery (E-TOS) in patients with T1-selected T3 pharyngeal and supraglottic cancers

Acta Oto-laryngologica
Yoshiki WatanabeTomoya Yamaguchi

Abstract

Endoscopic laryngo-pharyngeal surgery (ELPS), which is a transoral minimally invasive surgery using a gastrointestinal endoscope and a curved laryngopharyngeal retractor, is effective to treat primary lesions of superficial laryngopharyngeal cancers. To extend concepts of ELPS to invasive laryngopharyngeal cancers, we developed end-flexible-rigidscopic transoral surgery (E-TOS) from ELPS by changing a gastrointestinal endoscope to a flexible-tip rigid endoscope. To retrospectively evaluate oncological outcomes and laryngopharyngeal functional preservation of E-TOS in patients with T1-selected T3 laryngopharyngeal cancers. In 47 patients T1-selected T3 pharyngeal and supraglottic cancers were resected by E-TOS using the flexible-tip rigid endoscope and curved instruments. Negative resection margin was histopathologically evaluated. The survival, preservation of larynx, and disease control rates were estimated using Kaplan-Meier method. Curative resection was achieved in 94% of patients. No patient complained prolonged swallowing dysfunction or hoarseness after E-TOS. Postoperative bleeding, stenosis of the pharynx and esophageal entrance, and local recurrence was observed each in one patient. The 3-year overall survival, disease...Continue Reading

References

Mar 3, 2001·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·W SteinerM Kron
Jan 15, 2003·Archives of Otolaryngology--head & Neck Surgery·Wolfgang SteinerMartina Kron
Jul 5, 2005·The Laryngoscope·Gregory S WeinsteinNeil G Hockstein
Jul 14, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Manabu MutoShiegaki Yoshida
Aug 17, 2006·Nihon Jibiinkoka Gakkai kaiho·Yasuo SatouMunemasa Tagawa
Feb 20, 2007·The Annals of Otology, Rhinology, and Laryngology·Gregory S WeinsteinNeil G Hockstein
May 4, 2010·The Annals of Otology, Rhinology, and Laryngology·Akihiro ShiotaniKoichiro Saito
Apr 29, 2015·Surgical Endoscopy·Ichiro TateyaJuichi Ito
Sep 25, 2015·JAMA Otolaryngology-- Head & Neck Surgery·John R de AlmeidaF Christopher Holsinger
Aug 1, 2010·Journal of Robotic Surgery·Harry QuonGregory S Weinstein

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