Clinical outcomes of esophageal stents in patients with malignant esophageal obstruction according to palliative additional treatment

Journal of Digestive Diseases
Ji Yeon KimHyun Chae Jung

Abstract

To evaluate the efficacy and feasibility of esophageal self-expanding metal stents (SEMS) insertion for malignant esophageal obstruction (MEO) in patients with or without additional palliative treatment. We retrospectively reviewed the medical records of the patients with SEMS for MEO. Baseline characteristics, changes in Mellow-Pinkas dysphagia score, and adverse events were collected and compared according to the presence and absence of additional palliative treatment. Altogether 192 patients underwent 236 SEMS insertion procedures. Esophageal, gastric cardiac and lung cancers were seen in 46.4%, 33.3% and 15.1% of the patients, respectively. Their Mellow-Pinkas score significantly decreased within one week and one month after the SEMS insertion (1.66 ± 0.79 and 1.71  ±  0.87 vs 3.09  ±  0.79, respectively, P =  0.000). Complications occurred in 54 (22.9%) of 236 SEMS insertion; there were 28 (11.9%) stent obstruction, 5 (2.1%) perforation (2.1%), 10 (4.2%) stent migration, 5 (2.1%) tracheoesophageal fistula, but no procedure-related death. Most complications were managed by inserting additional SEMS. The risk of stent obstruction was significantly higher in uncovered stents than in covered SEMS (OR 3.56, 95% CI 1.39-9.12, P ...Continue Reading

References

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Citations

Oct 17, 2019·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J RoseiraA Dias Pereira
May 8, 2020·Journal of the National Comprehensive Cancer Network : JNCCN·Emily J MartinJames D Murphy
Nov 18, 2017·Digestive Diseases and Sciences·Hoonsub SoHwoon-Yong Jung
May 23, 2018·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·A KaneokaN Haga

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