Clinical outcomes of patients with papillary thyroid carcinoma after the detection of distant recurrence.

World Journal of Surgery
Yasuhiro ItoAkira Miyauchi

Abstract

Papillary thyroid carcinoma generally has an excellent prognosis but can have recurrence to the distant organs that is often life-threatening. To date, prognosis and prognostic factors of papillary carcinoma have been intensively investigated, but our knowledge regarding prognosis after the detection of distant recurrence remains inadequate. We investigated the prognosis and prognostic factors of papillary carcinoma after distant recurrence was detected during follow-up in a series of 105 patients who underwent locally curative surgery between 1987 and 2004. To date, 30 patients (29%) have died of carcinoma, and the 5-year and 10-year cause-specific survival (CSS) rates after the detection of distant recurrence were 71 and 50%, respectively. Patients aged 55 years or older at recurrence or with massive extrathyroid extension of primary lesions demonstrated a significantly worse CSS. On multivariate analysis, these two parameters were recognized as independent prognostic factors. Gender, tumor size, and lymph node metastasis did not affect patient prognosis. Uptake of radioactive iodine (RAI) to distant metastasis was not significantly linked to CSS, but none of the patients younger than aged 55 years showing RAI uptake died of ...Continue Reading

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Citations

Oct 12, 2012·Surgery Today·Hiroki UchidaTetsuya Kiuchi
Sep 6, 2012·Thyroid : Official Journal of the American Thyroid Association·Nikola BesicBarbara Gazic
Dec 1, 2011·Molecular Imaging and Radionuclide Therapy·Zekiye HasbekFadime Yumuk
Dec 6, 2014·Radiologic Clinics of North America·Jenny K HoangJorge D Oldan
Dec 31, 2015·Thyroid : Official Journal of the American Thyroid Association·Lawrence LeeJennifer H Kuo
Apr 30, 2013·Oral Oncology·Matthew J R Magarey, Jeremy L Freeman
Mar 1, 2012·Diagnostic Cytopathology·Christopher J VandenBusscheQing Kay Li
Nov 12, 2016·The International Journal of Biological Markers·Nae Yu KimWon Jin Cho
Aug 11, 2020·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Aline de Oliveira Ribeiro VianaLuiz Paulo Kowalski
Oct 21, 2015·Endocrinology and Metabolism·Tom Edward N LoPatricia Deanna D Maningat
Jan 1, 2012·American Society of Clinical Oncology Educational Book·A Dimitrios Colevas, Manisha H Shah
Jan 29, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Fangqin YuDetao Yin

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