Clinical outcomes of transcatheter aortic valve implantation in failed bioprosthetic surgical valves vs. native aortic stenosis: insights from a meta-analysis

Cardiovascular Intervention and Therapeutics
Fumiaki YashimaToshiki Kuno

Abstract

There is no meta-analysis comparing clinical outcomes between valve-in-valve transcatheter aortic valve implantation for failed surgical bioprosthetic valves (ViV-TAVI) and native valve TAVI for aortic stenosis (NV-TAVI). We aimed to investigate clinical outcomes between ViV-TAVI and NV-TAVI using a meta-analysis. EMBASE and MEDLINE were searched through April 2020 to investigate the comparative outcomes between ViV-TAVI and NV-TAVI. The main outcomes were short-term (30-day/in-hospital) mortality, pacemaker implantation (PMI), life threatening and/or major bleeding, stroke, and coronary obstruction, and long-term (1-year) mortality and stroke. Our search identified 5 observational studies enrolling a total of 8428 patients (1442 patients with ViV-TAVI and 6986 with NV-TAVI). ViV-TAVI was associated with significantly lower rates of short-term mortality, PMI, and life threatening and/or major bleeding, compared with NV-TAVI (relative risk [RR] [95% CI] 0.54 [0.34-0.84], P = 0.007; 0.25 [0.19-0.35], P < 0.0001; 0.64 [0.46-0.89], P = 0.008, respectively). There were no significant differences in rates of short-term stroke and coronary obstruction between ViV-TAVI and NV-TAVI (RR [95% CI] 0.59 [0.35-1.01], P = 0.06; 1.86 [0.78-4.4...Continue Reading

References

Oct 22, 2010·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER Trial Investigators
Jul 10, 2014·JAMA : the Journal of the American Medical Association·Danny DvirUNKNOWN Valve-in-Valve International Data Registry Investigators
Aug 9, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Kazuaki OkuyamaRaj Makkar
May 6, 2017·Journal of the American College of Cardiology·John G WebbMartin B Leon
May 20, 2017·JACC. Cardiovascular Interventions·G Michael DeebJeffrey J Popma
Jun 14, 2017·International Journal of Cardiology·Fumiaki YashimaKentaro Hayashida
Oct 25, 2017·Annals of Cardiothoracic Surgery·Vinayak Bapat
Jul 17, 2018·Journal of Interventional Cardiology·Zenon HuczekWojciech Wojakowski
Jul 22, 2018·Journal of the American College of Cardiology·E Murat TuzcuLars G Svensson
Aug 17, 2018·The Thoracic and Cardiovascular Surgeon·Hisato TakagiTomo Ando
Jan 29, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Enrico FerrariPeter Wenaweser
Mar 19, 2019·The New England Journal of Medicine·Michael J MackUNKNOWN PARTNER 3 Investigators
Jul 6, 2019·JACC. Cardiovascular Interventions·Robert J LedermanAdam B Greenbaum
Jul 11, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Amnon EitanJoachim Schofer
Jul 22, 2019·The American Journal of Cardiology·Hisato TakagiUNKNOWN ALICE (All-Literature Investigation of Cardiovascular Evidence) Group
Nov 5, 2019·The Canadian Journal of Cardiology·Anita W AsgarJohn G Webb
Jun 28, 2020·European Heart Journal·Sabine BleizifferDanny Dvir

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Citations

May 25, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Fumiaki YashimaGilbert H L Tang

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