Clinical outcomes resulting from the transfer of vitrified human embryos using a new device for cryopreservation (plastic blade).

Journal of Assisted Reproduction and Genetics
Rikikazu SugiyamaMasato Inoue

Abstract

We attempted clinical application of a plastic blade, which is a novel cryopreservation device, for vitrification of human embryos and blastocysts. Between February 2003 and December 2007, a total of 4,430 Day 3 embryos from 898 patients (Day 3 group) and 55 blastocysts from 29 patients (blastocyst group) were vitrified and cryopreserved with a plastic device, and subsequently thawed for embryo transfer. Clinical outcomes after thawing and transfer of vitrified embryos and blastocysts were evaluated. In the Day 3 group, all embryos resulting from 1,441 oocyte retrieval cycles were recovered, and the thawed embryo survival rate was 98.4%. In the blastocyst group, the survival rate after thawing was 100%. A total of 3,026 day 3 embryos and 46 blastocysts were transferred. The pregnancy and implantation rates in the Day 3 group were 25.0% and 15.5%, respectively, and in the blastocyst group the rates were 24.2% and 26.1%, respectively. The miscarriage rates in the Day 3 and blastocyst groups were 18.3% and 50.0%, respectively. A plastic blade is a useful novel device in cryopreservation of vitrified human embryos.

References

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Dec 26, 2008·Reproductive Medicine and Biology·Rikikazu SugiyamaMasato Inoue

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Citations

Apr 25, 2012·Journal of Assisted Reproduction and Genetics·Koji NakagawaRikikazu Sugiyama
Oct 27, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·Joseph Saragusty, Amir Arav
Jul 20, 2010·Journal of Assisted Reproduction and Genetics·Martin Graham WildingBrian Dale
Sep 23, 2010·Birth Defects Research. Part C, Embryo Today : Reviews·Wai Hung Tsang, King L Chow
May 4, 2017·American Journal of Reproductive Immunology : AJRI·Koji NakagawaKoushi Yamaguchi
Apr 3, 2014·The Journal of Obstetrics and Gynaecology Research·Koji NakagawaRikikazu Sugiyama
Sep 25, 2017·Journal of Assisted Reproduction and Genetics·MeiFang ZengLiuMing Li
Sep 25, 2020·Immunity, Inflammation and Disease·Keiji KurodaRikikazu Sugiyama
Oct 11, 2017·Animal Science Journal = Nihon Chikusan Gakkaihō·Ashit Kumar PaulRangsun Parnpai
Oct 17, 2014·Reproductive Medicine and Biology·Koji NakagawaRikikazu Sugiyama
Apr 10, 2021·American Journal of Reproductive Immunology : AJRI·Keiji KurodaRikikazu Sugiyama

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