PMID: 16629222Apr 25, 2006Paper

Clinical pathological correlates of renal biopsy in elderly patients

Clinical Nephrology
G FerroF Pizzarelli

Abstract

Reports have shown that well-defined histological patterns do not always correspond to equally clear clinical pictures, particularly so in elderly patients. With the aim of assessing clinicopathological correlations in the population aged >65 years with that of lower age, we retrospectively analyzed computerized records of renal needle biopsies consecutively performed in the decade 1991-2000 in our unit. Among the 392 eligible subjects, there were 150 patients 65 years of age and more, 76 of whom were over 70. The average serum creatinine was 2.9 mg/dl, with values > 3.5 mg/dl in 25% of cases. The major indication to biopsy was nephrotic syndrome followed by chronic renal failure both in the young adult and the elderly population. The rapidly progressive form led more often to renal biopsy in the elderly patients, and the different prevalence was statistically significant (p < 0.05), as was the higher prevalence of urinary anomalies in the young-adult population. Regarding renal histology, the crescentic necrotizing forms were significantly more frequent in the elderly patients, while IgAN, minimal change disease and SLE predominate in young adults. The most relevant result is the greater prevalence of crescentic necrotizing gl...Continue Reading

Citations

Nov 30, 2010·International Urology and Nephrology·Nasreen Mohamed, Rohan John
Feb 22, 2012·American Journal of Nephrology·Eduardo VerdeJuan M López-Gómez
Sep 12, 2013·American Journal of Nephrology·Zhi-Yu DuanXiang-Mei Chen
Jun 11, 2008·Drugs & Aging·Ching M CheungJohn G Anderton
May 16, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Dimitrios-Anestis MoutzourisVivette D D'Agati
Jul 19, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Bo JinZhihong Liu
Oct 12, 2012·Clinical and Experimental Nephrology·Hitoshi YokoyamaUNKNOWN Committee for the Standardization of Renal Pathological Diagnosis and for Renal Biopsy and Disease Registry of the Japanese
Mar 8, 2014·Advances in Chronic Kidney Disease·Qi Qian, Samih H Nasr
Mar 28, 2012·Advances in Chronic Kidney Disease·Andrew S BombackGlen S Markowitz
Mar 3, 2015·Nephrology·Wisit CheungpasitpornQi Qian
Nov 21, 2017·Nephrology·Jing LinQi Qian
Mar 5, 2019·International Urology and Nephrology·Murat TuğcuGülistan Gümrükçü
Jul 3, 2015·International Urology and Nephrology·Ozlem HarmankayaMehmet Hursitoglu
Mar 3, 2020·International Urology and Nephrology·Martin PlanchaisAnne-Sophie Garnier
Dec 5, 2020·Indian Journal of Nephrology·Pankaj BeniwalSanjeev Sharma

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