Clinical performance of a rapid influenza test and comparison of nasal versus throat swabs to detect 2009 pandemic influenza A (H1N1) infection in Thai children

The Pediatric Infectious Disease Journal
Piyarat SuntarattiwongJames M Simmerman

Abstract

We identified febrile pediatric outpatients seeking care for influenza like illness in Bangkok. Two nasal and 1 throat swab were tested using the QuickVue A+B rapid influenza kit and reverse transcription-polymerase chain reaction. Among 142 pandemic influenza A (H1N1)-positive patients, the QuickVue test identified 89 positive tests for a sensitivity of 62.7% (95% confidence interval [CI]: 54.7-70.6). Specificity was 99.2% (95% CI: 98-100). In the 0 to 2 years age group, sensitivity was 76.7% (95% CI: 61.5-91.8). Throat and nasal swabs are equally useful diagnostic specimens for reverse transcription-polymerase chain reaction diagnosis.

Associated Clinical Trials

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Citations

Apr 12, 2012·Clinical Microbiology Reviews·Vincent C C ChengKwok-Yung Yuen
Apr 12, 2012·Clinical Microbiology Reviews·Swati Kumar, Kelly J Henrickson
Jun 18, 2010·Journal of Clinical Microbiology·Yuko Sakai-TagawaYoshihiro Kawaoka
Apr 20, 2012·PloS One·Brendan KlickBenjamin J Cowling
Apr 15, 2011·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·G NoelP Minodier
Apr 23, 2010·Emerging Infectious Diseases·Janice K LouieDavid P Schnurr
Aug 9, 2012·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Chang Kyu LeeWoo Joo Kim
May 19, 2010·The Journal of School Nursing : the Official Publication of the National Association of School Nurses·Carolyn Herl JenlinkDonna Mazyck
Nov 3, 2009·Annals of Thoracic Medicine·N PetrosilloE Grilli
Mar 5, 2016·Folia medica·Golubinka BosevskaZvonko Milenkovik
Jun 28, 2011·Journal of Dental Research·L BilderF Basis
Sep 3, 2011·Influenza and Other Respiratory Viruses·Haitao ChuStephen R Cole

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