Clinical predictors of antibiotic prescribing for acutely ill children in primary care: an observational study
Abstract
Antibiotic overuse and inappropriate prescribing drive antibiotic resistance. Children account for a high proportion of antibiotics prescribed in primary care. To determine the predictors of antibiotic prescription in young children presenting to UK general practices with acute illness. Prospective observational study in general practices in Wales. A total of 999 children were recruited from 13 practices between March 2008 and July 2010. Multilevel, multivariable logistic regression analysis was performed to determine predictors of antibiotic prescribing. Oral antibiotics were prescribed to 261 children (26.1%). Respiratory infections were responsible for 77.4% of antibiotic prescriptions. The multivariable model included 719 children. Children were more likely to be prescribed antibiotics if they were older (odds ratio [OR] 1.3; 95% confidence intervals [CI] = 1.1 to 1.7); presented with poor sleep (OR 2.7; 95% CI = 1.5 to 5.0); had abnormal ear (OR 6.5; 95% CI = 2.5 to 17.2), throat (OR 2.2; 95% CI = 1.1 to 4.5) or chest examination (OR 13.6; 95% CI = 5.8 to 32.2); were diagnosed with lower respiratory tract infection (OR 9.5; 95% CI = 3.7 to 25.5), tonsillitis/sore throat (OR 119.3; 95% CI = 28.2 to 504.6), ear infection (OR...Continue Reading
References
Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
Understanding physician antibiotic prescribing behaviour: a systematic review of qualitative studies
An association between socioeconomic deprivation and primary care antibiotic prescribing in Scotland
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