Clinical predictors of long-term outcomes in patients with critical limb ischemia who have undergone endovascular therapy

Angiology
Shang-Hung ChangHsuan-Li Huang

Abstract

Clinical predictors of long-term outcomes in patients with critical limb ischemia (CLI) treated with endovascular therapy (EVT) remain unclear. In this study, clinical predictors of long-term outcomes in EVT-treated patients with CLI were investigated. In this prospective, observational study, we analyzed a total of 253 Taiwanese patients with CLI with 314 limbs who underwent EVT between 2005 and 2012. Cox models were used to estimate hazard ratios of death, limb loss, and sustained clinical success (SCS). Multivariate analysis showed that age, atrial fibrillation (AF), end-stage renal disease (ESRD), and albumin were significant predictors of mortality. Patients with coronary artery disease and low albumin levels had a significant risk of major limb amputation, while AF, ESRD, and albumin were significant, independent predictors of SCS. In addition to previously reported predictors, we showed that AF and malnutrition can be used to predict long-term outcome in EVT-treated patients with CLI.

References

Sep 24, 2004·Current Drug Targets. Cardiovascular & Haematological Disorders·S NovoG Milio
Oct 9, 2004·Journal of Vascular Surgery·Jyrki VirkkunenUNKNOWN Finnvasc Study Group
Mar 7, 2006·Journal of the American College of Cardiology·Steven P Marso, William R Hiatt
Jul 1, 2006·Journal of General Internal Medicine·Meggan R BantaDaniel G Federman
Jul 11, 2006·Journal of Vascular Surgery·William A MarstonBlair A Keagy
Aug 16, 2006·Circulation·Beatrice A GolombMichael H Criqui
Jan 16, 2007·Journal of Vascular Surgery·L NorgrenUNKNOWN TASC II Working Group
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Ann M O'HareMary-Margaret Chren
Mar 29, 2008·Journal of Vascular Surgery·Marcello RomitiNelson De Luccia
May 6, 2008·The American Surgeon·Spence M Taylor
Jul 1, 2008·Journal of Vascular Surgery·John S LaneSheldon Greenfield
Jul 22, 2008·Chest·Wael GalalDon Poldermans
Feb 2, 2010·Journal of Vascular Surgery·Vinit N VaruMelina R Kibbe
Apr 14, 2010·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T A WinkelD Poldermans
Sep 21, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Kuan-Hung YehYu-Lin Ko
Apr 26, 2011·Journal of Vascular Surgery·Monica S O'Brien-IrrMaciej L Dryjski
Aug 13, 2011·Annals of Vascular Surgery·Bharath N Kumar, Raghvinder Pal S Gambhir
Nov 7, 2012·VASA. Zeitschrift für Gefässkrankheiten·C KöhlerN Weiss
Jan 2, 2013·Angiology·Nezar Falluji, Debabrata Mukherjee
Feb 5, 2013·Journal of Vascular Surgery·Ruby C LoMarc L Schermerhorn
May 1, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshimitsu SogaUNKNOWN ReCANALISE Investigators
Jul 11, 2013·Angiology·Adriano Sala TennaGerard Stansby

❮ Previous
Next ❯

Citations

Jan 25, 2014·Angiology·Elias E MazokopakisEmmanouel S Ganotakis
Aug 25, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Akio KodamaKimihiro Komori
May 25, 2018·International Angiology : a Journal of the International Union of Angiology·Mireia MartínezAlbert Clarà
Feb 14, 2020·International Angiology : a Journal of the International Union of Angiology·Marta Spychalska-ZwolińskaJacek Budzyński
Apr 20, 2021·Expert Review of Cardiovascular Therapy·Stefanos Giannopoulos, Ehrin J Armstrong

❮ Previous
Next ❯

Methods Mentioned

BETA
amputation
amputations
percutaneous transluminal angioplasty

Software Mentioned

SAS

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.