Clinical Presentation, Management, and Outcomes of Deep Vein Thrombosis Based on Doppler Ultrasonography Examination

Angiology
Hassan Al-ThaniAbdul Salim Kiliyanni

Abstract

We studied the frequency, clinical presentation, and outcomes of deep vein thrombosis (DVT). Serial Doppler ultrasonography was performed between 2008 and 2013 for 6420 patients with suspected DVT. Diagnosis was confirmed in 662 (10.3%) participants (mean age: 50 ± 17 years; 51% females). Obesity, diabetes mellitus, and malignancy were reported in 47%, 28%, and 16%, respectively. Abnormal protein C, protein S, factor V Leiden, or antithrombin III were found in 9%, 7%, 3.8%, and 4%, respectively. Left, right, and both legs were involved in 55%, 37%, and 8%, respectively. Common femoral, popliteal, and posterior tibial veins were affected in 48.5%, 72%, and 71%, respectively. Postthrombotic syndrome, pulmonary embolism, and death were reported in 50%, 12.2%, and 15% of cases, respectively. Kaplan-Meier survival curves and Cox regression analysis showed that gender had no impact on mortality during follow-up; however, age (>50 years) was associated with greater risk of death (hazard ratio: 6.54; 95% confidence interval: 3.2-13.3). These findings will improve our understanding of the various risk factors and help develop institutional guidelines for the management of patients with DVT.

References

Aug 1, 1992·Journal of Internal Medicine·M NordströmT Kjellström
Jun 1, 1974·The British Journal of Surgery·I G Cunningham, N K Yong
Jun 1, 1983·The American Journal of Medicine·S Z GoldhaberM Feinleib
Sep 9, 1983·JAMA : the Journal of the American Medical Association·D E StrandnessB L Thiele
Nov 1, 1995·Journal of Vascular Surgery·H G BeebeM J Vitti
Jan 24, 1994·Archives of Internal Medicine·A CogoA Girolami
Mar 29, 2000·Archives of Internal Medicine·P O HanssonH Eriksson
May 22, 2002·Archives of Internal Medicine·Susan R KahnIan Shrier
Jun 1, 2002·Archives of Internal Medicine·John A HeitL Joseph Melton
Jun 11, 2003·Archives of Internal Medicine·Bengt I ErikssonUNKNOWN PENTasaccharide in HIp-FRActure Surgery Plus Investigators
Jun 20, 2003·Circulation·Richard H White
Jun 20, 2003·Circulation·Frederick A Anderson, Frederick A Spencer
Sep 26, 2003·The New England Journal of Medicine·Philip S WellsMichael J Kovacs
Oct 3, 2003·Journal of Thrombosis and Haemostasis : JTH·A van Hylckama Vlieg, F R Rosendaal
Nov 7, 2003·Journal of Vascular Surgery·Juan I ArcelusJosé González-Fajardo
Mar 30, 2004·The British Journal of Surgery·B L Y CheukS W K Cheng
Mar 31, 2004·Circulation·Brenda K Zierler
Apr 22, 2004·Clinics in Chest Medicine·Lisa MooresSusan Murin
Nov 26, 2004·Journal of Clinical Pathology·R AlikhanA T Cohen
Jun 28, 2005·Journal of Thrombosis and Haemostasis : JTH·G Di MinnoUNKNOWN First Ambulatory Screening On Thromboembolism (fast) Study Group
Feb 14, 2006·Journal of Thrombosis and Thrombolysis·Stephan Moll
Jun 7, 2006·Annals of Internal Medicine·Clive KearonUNKNOWN Canadian Pulmonary Embolism Diagnosis Study (CANPEDS) Group
Dec 19, 2007·Circulation·Walter AgenoPieter W Kamphuisen
Feb 27, 2008·Archives of Internal Medicine·Frederick A SpencerRobert J Goldberg
Apr 11, 2008·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Faisal Al SayeghMaha Al Farhan
Jul 31, 2008·Journal of Thrombosis and Haemostasis : JTH·E Roseann AndreouC Kearon
Dec 20, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Masahito SakumaTakao Kobayashi
Jul 8, 2009·Annals of Internal Medicine·Divay ChandraDariush Mozaffarian
Jul 1, 2010·Journal of Thrombosis and Haemostasis : JTH·W ThijsS Middeldorp
Jul 16, 2010·Journal of Thrombosis and Haemostasis : JTH·M J EngbersF R Rosendaal
May 9, 2012·The American Journal of Medicine·Gregory PiazzaFrederick A Spencer
Jan 1, 2011·Journal of the Turkish German Gynecological Association·K Mehmet BurgazlıA Kubilay Ertan

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Citations

Jan 12, 2017·Phlebology·Ayman El-MenyarHassan Al-Thani
Sep 8, 2017·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Ayman El-MenyarHassan Al-Thani

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Methods Mentioned

BETA
hormone replacement therapy
surgical resection

Software Mentioned

SPSS

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