Clinical presentation of inappropriate sinus tachycardia and differential diagnosis

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing
Michael Peyrol, Samuel Lévy

Abstract

Inappropriate sinus tachycardia (IST) is a syndrome characterized by a sinus tachycardia not related to a medical condition, to a physiological response, or to medication or drugs and associated with symptoms, often invalidating and altering the quality of life of affected patients. It occurs predominantly in adolescents and young adults, and in the female sex. The diagnosis requires a complete work-up in order to exclude other causes of sinus tachycardia and one or several additional tests: 24-h ECG ambulatory recordings, echocardiogram, exercise testing, and autonomous nervous system assessment. It should be differentiated from the postural orthostatic tachycardia syndrome, with which it shares a number of symptoms, and other supraventricular tachycardias originating in the high right atrium. An electrophysiological study should be considered in selected cases in order to differentiate IST from other supraventricular tachycardias. The mechanism is still unclear, and possible etiologies may include intrinsic abnormality of the sinus node, autonomic dysfunction, hypersensitivity of the sinus node to catecholamines, blunted vagal system, or a combination of the above. The authors emphasize the wide spectrum of clinical presentat...Continue Reading

References

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Citations

Jul 3, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Cecilia LindeUNKNOWN ESC Scientific Document Group
Aug 8, 2020·BMC Pediatrics·Monika Wójtowicz-MarzecMaria Respondek-Liberska
Dec 22, 2020·Obstetric Medicine·Priyanka Kugamoorthy, Danna A Spears
Feb 11, 2021·Journal of Cardiovascular Electrophysiology·Samuel A ShabtaieSamuel J Asirvatham

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