Abstract
Acute kidney injury (AKI) requiring renal replacement therapy is associated with high mortality. The study assessed the impact of the introduction of hemodialysis (HD) on outcomes of patients with AKI in Rwanda. A single center retrospective study that evaluated the clinical profile and survival outcomes of patients with AKI requiring HD [AKI-D] at a tertiary hospital in Rwanda. Data was collected on patients who received HD for AKI from September 2014 to December 2016. Patient demographics, comorbidities, clinical presentation, laboratory tests, and mortality were reviewed and analyzed. Predictors of mortality were assessed using age and gender adjusted multivariate analyses. Of the 82 eligible patients, median age was 38 years (IQR 28-57 years). Males comprised 51% of the cohort. Infectious diseases including malaria, pneumonia, and sepsis (35.1%) and pregnancy-related conditions (26.9%) were the most frequent comorbidities. Pulmonary oedema (54.9%) and uremic encephalopathy (50%) were top indications for HD. Mortality was 34.1%. On multivariate analysis, receipt of <5 sessions of HD (OR = 4.01, 95% CI 1.185-13.61, P = 0.026) and hyperkalemia (OR = 3.23, 95% CI 1.040-10.065, P = 0.043) were associated with mortality. The avai...Continue Reading
References
Mar 1, 1995·Renal Failure·I G RandereeI P Naiker
Dec 1, 1996·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J PrakashP K Srivastava
Jan 24, 2008·Nature Clinical Practice. Nephrology·Jorge CerdáRajasekara M Chakravarthi
Jul 16, 2008·Seminars in Nephrology·Saraladevi NaickerMohamed Benghanem Gharbi
May 3, 2013·Kidney International·Andrew J P LewingtonRavindra L Mehta
Nov 14, 2013·Clinical Nephrology·Lobna Ben MahmoudKhaled Zeghal
Jan 17, 2015·BMC Nephrology·Peace BagashaRobert Kalyesubula
Mar 18, 2015·Lancet·Ravindra L MehtaGiuseppe Remuzzi
Jul 30, 2016·Clinical Nephrology·Dwomoa AduCharlotte Osafo
Oct 19, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Garabed Eknoyan
Jan 16, 2017·BMC Nephrology·Rhys D R EvansGavin Dreyer
Jul 27, 2017·BioMed Research International·Sasa NieXiangmei Chen
Aug 6, 2017·Advances in Chronic Kidney Disease·Simon Sawhney, Simon D Fraser
Citations
Jul 6, 2018·Nursing Research and Practice·Marie Claire MukakarangwaGodfrey Katende
Mar 7, 2020·Pharmacological Reports : PR·Diaa RagabHanan S El-Abhar
Jul 11, 2020·KI Reports·Grace IgiranezaAsghar Rastegar
Jun 15, 2018·Biochemical and Biophysical Research Communications·Bassim I MohammadHayder A Al-Aubaidy