PMID: 2512117Nov 1, 1989Paper

Clinical profile of partial seizures beginning at less than four years of age

Epilepsia
W T Blume

Abstract

Clinical features of all our 46 patients whose recurrent partial seizures began at age less than or equal to 47 months were studied. Thirty-seven (80%) had motor seizures which were exclusively unilateral in 14 patients, bilaterally synchronous in 8, and both unilateral and bilaterally synchronous in 15. Thirty-three patients (72%) had complex partial seizures (CPS), and 11 patients (24%) had simple partial somatosensory seizures. Clinical seizures were recorded by EEG in 18 patients (39%), and a subclinical (larval) seizure was recorded in 1; those in 10 patients arose from a temporal lobe, 4 were from a frontal lobe, and in 5 they involved two adjacent lobes from onset. Several extra-ictal features reliably indicated lobe or hemisphere of seizure onset. The lobe of principal interictal EEG spikes corresponded to seizure origin in 33 of 34 patients (97%), and regional delta activity corresponded to lobe of seizure origin in 22 of 24 patients (92%). The seizures of all 13 patients with unilateral neurologic signs corresponded to the hemisphere implicated by the deficit. Computed tomography (CT) scan showed lesions in 30 patients (65%) and corresponded to the lobe of seizure onset in 27 of the 30 (90%). Seizures arose primarily ...Continue Reading

References

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Citations

Jun 14, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dean P SarcoJoseph R Madsen
Oct 24, 2002·Pediatric Neurology·Sanjay ChawlaVenkatesan Mallika
Jun 1, 1994·Seizure : the Journal of the British Epilepsy Association·E F Staufenberg, S W Brown
Apr 21, 1998·Seminars in Pediatric Neurology·R D Sheth
Sep 14, 2001·Epilepsia·D R NordliL J Hirsch
Aug 16, 2002·Epilepsia·Kristina KällénPrakash Kotagal
May 1, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·E J Novotny
Nov 1, 1993·Epilepsia·R B May, T R Sunder
May 1, 1993·Epilepsia·S Sveinbjornsdottir, J S Duncan
May 1, 1994·Epilepsia·A M Bye, S Foo
Dec 22, 2011·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Lakshmi NagarajanSoumya Ghosh
Feb 6, 2008·Clinical Neurology and Neurosurgery·Amira MasriAbdelkarim A Al-Qudah
Oct 16, 1999·Seminars in Pediatric Neurology·P Singhi, M Ray
Jul 4, 2007·Arquivos de neuro-psiquiatria·Maria Augusta MontenegroMarilisa M Guerreiro
Oct 6, 2001·Revista de neurologia·J C Sánchez-Alvarez, A Altuzarra-Corral
Dec 7, 2000·Journal of Child Neurology·J M WilmshurstP J Grattan-Smith
Jan 1, 1992·Journal of Child Neurology·M Duchowny
Sep 1, 1995·Developmental Medicine and Child Neurology·P CuratoloE Medda
Jan 1, 1993·Epilepsia·G L Holmes
Jul 4, 2001·Pediatrics·D R NordliD C De Vivo

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