PMID: 8949437Sep 1, 1996Paper

Clinical reactions to systemic provocation with gold sodium thiomalate in patients with contact allergy to gold

The British Journal of Dermatology
H MöllerMagnus Bruze

Abstract

In a double blind experimental study, 20 patients with a contact allergy to gold sodium thiosulphate were challenged intramuscularly with the chemically similar gold sodium thiomalate and with placebo. The most spectacular clinical reaction in the 10 patients given the active agent, was an epidermal and dermal flare up of healed patch-test reactions to the gold salts, as well as a high, but transient, rise in body temperature. Previous intradermal tests were similarly reactivated. In addition, toxicoderma-like rashes were observed in several cases, but a flare up of a previous contact dermatitis site was seen in one patient only. The specificity of the positive provocations was demonstrated.

References

Jun 1, 1975·Contact Dermatitis·O B Christensen, H Möller
Nov 27, 1976·British Medical Journal·J A Rennie
Jan 1, 1992·Archives of Dermatological Research·G Swanbeck, E Dahlberg
Feb 1, 1982·Annals of the Rheumatic Diseases·R A FultonH Capell
Jan 1, 1995·Contact Dermatitis·M BruzeH Möller
Mar 1, 1995·Contact Dermatitis·K E McKennaD Burrows
Oct 1, 1994·Journal of the American Academy of Dermatology·M BruzeH Möller
Dec 1, 1995·Contact Dermatitis·M BruzeH Möller

❮ Previous
Next ❯

Citations

Aug 1, 1997·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J J Hostýnek
Jul 1, 1997·Clinics in Dermatology·N K Veien
Apr 4, 1998·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·H MöllerM Bruze
Apr 16, 1998·Contact Dermatitis·C FlemingR MacKie
Jul 17, 1998·Contact Dermatitis·J A MarcussonJ Heilborn
Nov 9, 2002·Contact Dermatitis·Halvor Möller
Feb 28, 2002·BMC Dermatology·Ake SvenssonCarina Linder
May 4, 2010·Contact Dermatitis·Halvor Möller

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.