Clinical recognition of allodynia in migraine

Neurology
Ninan T MathewTad Seifert

Abstract

Allodynia, a manifestation of central sensitization, is not routinely evaluated during clinical interviews even though its therapeutic implications are known. To assess the frequency and manifestations of allodynia in a clinic-based migraine population. A total of 295 consecutive International Headache Society migraine patients were evaluated using a semistructured questionnaire. A total of 157 (53.3%) reported allodynia. A total of 133 (84.7% of those with allodynia) had cephalic, 54 (18%) had both cephalic and extracephalic, and 24 (8.5%) exhibited pure extracephalic allodynia. Prominent scalp symptoms were sensitivity to touch; soreness or tenderness; difficulty brushing, combing, or washing hair; difficulty lying with head resting on the side of allodynia; and circumscribed area of hypersensitivity and tenderness. Scalp allodynia was ipsilateral to predominant headache side in the majority and occurred at the height of headache. Extracephalic allodynia of the upper extremities occurred in 72, toes in 6. Truncal allodynia occurred in some. Age range and age at onset of migraine were identical in allodynic and non-allodynic patients. Patients with allodynia were on an average 8 years older than non-allodynic patients (p < 0.0...Continue Reading

Citations

Jun 1, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marco Aguggia
Nov 28, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Hayat GüvenSelim Selçuk Çomoğlu
May 25, 2013·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marco AguggiaP Cortelli
Sep 27, 2007·Current Pain and Headache Reports·Paola SarchielliPaolo Calabresi
Dec 20, 2008·Current Treatment Options in Neurology·William B Young
Dec 14, 2005·Current Treatment Options in Neurology·Robert Kaniecki
Oct 2, 2013·Brain : a Journal of Neurology·Mark A LouterGisela M Terwindt
Jun 22, 2006·The Clinical Journal of Pain·César Fernández-de-Las-PeñasJuan A Pareja
May 21, 2009·The Clinical Journal of Pain·César Fernández-de-las-PeñasJuan A Pareja
Nov 19, 2009·The Clinical Journal of Pain·Jayantee KalitaUsha Kant Misra
Jan 19, 2013·The Clinical Journal of Pain·Usha K MisraSanjeev K Bhoi
Feb 15, 2012·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Kathleen B Digre, K C Brennan
Dec 21, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C Fernández-de-Las-PeñasJ A Pareja
Sep 18, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·T SandL J Stovner
Dec 11, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M Schürks, H-C Diener
Mar 25, 2006·Cephalalgia : an International Journal of Headache·G IferganeH Cohen
Aug 22, 2006·Cephalalgia : an International Journal of Headache·J LaddaT Eggert
Aug 22, 2006·Cephalalgia : an International Journal of Headache·C Fernández-de-Las-PeñasJ A Pareja
Jan 30, 2007·Cephalalgia : an International Journal of Headache·A AshkenaziW B Young
Nov 21, 2007·Cephalalgia : an International Journal of Headache·M L CuadradoJ A Pareja
Jul 23, 2008·Cephalalgia : an International Journal of Headache·J SchoenenUNKNOWN Belgian Headache Society
Nov 6, 2009·Cephalalgia : an International Journal of Headache·C Fernández-de-las-PeñasJ A Pareja
Sep 11, 2009·Cephalalgia : an International Journal of Headache·N GuyP Clavelou
Oct 2, 2012·Annals of Indian Academy of Neurology·K Ravishankar
Apr 18, 2013·Current Opinion in Neurology·Todd J Schwedt
Jun 9, 2005·Expert Review of Neurotherapeutics·Stephen H Landy, Bob L Lobo
Nov 4, 2015·Toxins·Min HouYi-Ping Hou
Mar 11, 2009·Expert Review of Neurotherapeutics·Carlo LovatiPierluigi Bertora
May 12, 2007·Expert Review of Neurotherapeutics·Frederick G Freitag
Jan 16, 2008·Journal of the Chinese Medical Association : JCMA·Yi-Chung LiuShuu-Jiun Wang
Jan 23, 2016·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Jenny L LauschkeClare L Fraser
Oct 1, 2013·The Journal of Emergency Medicine·Carlos J Roldan
Feb 4, 2016·Pain Research and Treatment·Rubesh GooriahFayyaz Ahmed
May 8, 2009·The Journal of Headache and Pain·Michael J MarmuraAvi Ashkenazi
Jul 14, 2010·The Journal of Headache and Pain·Ilya KisterR B Lipton
Jan 25, 2008·The Journal of Headache and Pain·Andrea Stephanie LinkLars Edvinsson
Jul 6, 2007·The Journal of Pain : Official Journal of the American Pain Society·Paola SarchielliPaolo Calabresi
Oct 1, 2009·Headache·Gretchen E TietjenSadik A Khuder
Jan 8, 2009·Headache·Timothy MaddenWilliam Young
Feb 29, 2008·Annals of Neurology·Andrew Charles, K C Brennan
Dec 7, 2007·Annals of Neurology·Richard B LiptonUNKNOWN American Migraine Prevalence Prevention Advisory Group

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