Clinical relevance of antimicrobial resistance in the management of pneumococcal community-acquired pneumonia

The Journal of Laboratory and Clinical Medicine
Charles Feldman

Abstract

Streptococcus pneumoniae remains the most common bacterial cause of community-acquired pneumonia, and these infections are associated with significant morbidity and mortality worldwide. A major concern is the increasing incidence of antibiotic resistance among pneumococcal isolates, which, in the case of certain of the antibiotic classes, has been associated with treatment failure. Yet despite multiple reports of infections with penicillin-resistant pneumococcal isolates, no cases of bacteriologic failure have been documented with the use of penicillin or ampicillin in the treatment of pneumonia caused by penicillin-resistant pneumococci. Current prevalence and levels of penicillin resistance among pneumococal isolates in most areas of the world do not indicate a need for substantial treatment changes with regard to the use of the penicillins. For infections with penicillin-sensitive strains, penicillin or an aminopenicillin in a standard dosage will still be effective for treatment. In the cases of strains with intermediate resistance, beta-lactam agents are still considered appropriate treatment, although higher dosages are recommended. Infections with isolates of high-level penicillin resistance should be treated with altern...Continue Reading

References

May 23, 2012·Proceedings of the National Academy of Sciences of the United States of America·Janwillem DuitmanC Arnold Spek
Jun 7, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Carrie L ByingtonAndrew T Pavia
Feb 16, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Imad M TleyjehLarry M Baddour
Mar 11, 2009·Respirology : Official Journal of the Asian Pacific Society of Respirology·Charles Feldman, Ronald Anderson
Dec 17, 2009·Journal of Clinical Microbiology·Tomer AvniMical Paul
Dec 18, 2008·Malaria Journal·R Matthew ChicoDaniel Chandramohan
Feb 1, 2011·Drugs·Charles Feldman, Ronald Anderson
Jul 31, 2007·Future Microbiology·Charles Feldman, Ronald Anderson
Jan 19, 2008·The American Journal of Pathology·Sarah L FarnworthTariq Sethi
Jul 15, 2009·Immunological Reviews·Neil C Henderson, Tariq Sethi
Apr 23, 2014·The Journal of Pathology·Tijmen J HommesTom van der Poll
Nov 11, 2006·Médecine et maladies infectieuses·P Chavanet, D Croisier
Jan 19, 2008·Expert Opinion on Pharmacotherapy·Javier AspaFelipe Rodríguez de Castro
Oct 3, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J PradelliP-M Roger
Apr 19, 2016·International Journal of Molecular Sciences·Szu-Chia Chen, Po-Lin Kuo
Sep 10, 2014·Biotechnology and Applied Biochemistry·Ling ChenJianhua Zhang
Nov 14, 2018·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Bidisha UkilLarisha Mawkhlieng Lyndem
Feb 19, 2009·Tropical Medicine & International Health : TM & IH·Elizeus RutebemberwaGeorge Pariyo
Nov 21, 2012·The American Journal of Tropical Medicine and Hygiene·Yolanda Barberá LaínezEmmanuel D'Harcourt
Jan 3, 2013·The American Journal of Tropical Medicine and Hygiene·Elizeus RutebemberwaGeorge Pariyo
Nov 21, 2012·The American Journal of Tropical Medicine and Hygiene·Humphreys NsonaTexas Zamasiya
Jan 3, 2013·The American Journal of Tropical Medicine and Hygiene·Laura McGormanAsha George
Nov 21, 2012·The American Journal of Tropical Medicine and Hygiene·Phyllis AworStefan Peterson
Jan 3, 2013·The American Journal of Tropical Medicine and Hygiene·Agnes Nanyonjo The inSCALE Study Group
May 4, 2011·Reproduction in Domestic Animals = Zuchthygiene·B H SontasA Mollo
Nov 16, 2010·Expert Review of Anti-infective Therapy·Brian Wispelwey, Katherine R Schafer

Citations

Jan 10, 1996·JAMA : the Journal of the American Medical Association·M J FineW N Kapoor
Dec 24, 1997·Chest·C S BryanM S Stinson
Feb 10, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W A Craig
Jun 24, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E H Choi, H J Lee
Jun 3, 1999·American Journal of Respiratory and Critical Care Medicine·S EwigJ Mensa
Aug 18, 1999·The American Journal of Medicine·Maurice A Mufson, Ronald J Stanek
Aug 24, 1999·Annals of Internal Medicine·M J KuehnertC A Perlino
Aug 25, 1999·The Journal of Antimicrobial Chemotherapy·G W Amsden
Sep 7, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G S TurettE E Telzak
Sep 7, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S F DowellJ Snitzer
Feb 10, 2000·American Journal of Public Health·D R FeikinJames H Jorgensen
Mar 7, 2000·The Journal of Antimicrobial Chemotherapy·E Pérez-Trallero
Mar 18, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joshua P MetlayR F Breiman
Mar 23, 2000·Respirology : Official Journal of the Asian Pacific Society of Respirology·H WatanabeT Nagatake
Sep 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J G BartlettM J Fine
Sep 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C FogartyK Bush
Oct 26, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M A KelleyM S Cohen
Dec 5, 2000·The Journal of Antimicrobial Chemotherapy·H K JohansenN Frimodt-Moller
Mar 7, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P L HoR M Chan
Mar 16, 2001·Current Opinion in Investigational Drugs·J F Barrett
Jun 13, 2001·American Journal of Respiratory and Critical Care Medicine·M S NiedermanAmerican Thoracic Society
Jul 20, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M PihlajamäkiFinnish Study Group for Antimicrobial Resistance (FiRe-Network)
Aug 30, 2001·Archives of Internal Medicine·G W WatererR G Wunderink
Aug 21, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J F MoroneyA Schuchat
Aug 23, 2001·The Journal of Infectious Diseases·C UrbanJ J Rahal
Oct 26, 2001·JAMA : the Journal of the American Medical Association·T B HydeActive Bacterial Core Surveillance/Emerging Infections Program Network
Dec 26, 2001·Archives of Internal Medicine·Daniel M MusherGary V Doern
Dec 12, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M R Jacobs
Jan 26, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert C Moellering
Jan 26, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas M File
Jan 26, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph P Lynch III, Fernando J Martinez
Feb 19, 2002·Antimicrobial Agents and Chemotherapy·Angela B BrueggemannGary V Doern
Feb 22, 2002·The New England Journal of Medicine·Daniel M MusherKurt L Krause
Feb 28, 2002·The Journal of Antimicrobial Chemotherapy·William Bishai
Mar 8, 2002·The New England Journal of Medicine·Ross DavidsonDonald E Low
Apr 20, 2002·Current Opinion in Infectious Diseases·Joshua P Metlay
Apr 30, 2002·Current Opinion in Infectious Diseases·K P Klugman, Charles Feldman

Related Concepts

Tetracycline Antibiotics
Meropenem
Microorganism
Gatifloxacin
Fluoroquinolone antiinfectives, ophthalmologic
Tetracyclines
Morbidity Aspects
beta-Lactams
Erythromycin
Fluoroquinolones

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Meningitis

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Meningitis (ASM)

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Constance D Rothermel
Current Infectious Disease Reports
Michael Henry, Howard L. Leaf
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
M W R PletzK P Klugman
Seminars in Respiratory and Critical Care Medicine
Joseph P Lynch, George G Zhanel
© 2020 Meta ULC. All rights reserved