Clinical results of ab interno trabeculotomy using the trabectome for open-angle glaucoma: the Mayo Clinic series in Rochester, Minnesota

American Journal of Ophthalmology
Yachna AhujaArthur J Sit

Abstract

To determine outcomes of ab interno trabeculotomy for treatment of open-angle glaucoma (OAG). Retrospective interventional single-surgeon, single-center case series. Data were collected from 246 patients undergoing ab interno trabeculotomy between September 1, 2006, and December 1, 2010, with 3 months' follow-up or longer. Kaplan-Meier analysis was performed using Criteria A (postoperative intraocular pressure [IOP] ≤21 mm Hg or ≥20% reduction from preoperative IOP) and Criteria B (IOP ≤18 mm Hg and ≥20% reduction in IOP). Failure included increased glaucoma medications or subsequent surgery. Failure risk factors were identified using Cox proportional hazards ratio (HR). Of 88 cases of ab interno trabeculotomy-only and 158 cases of ab interno trabeculotomy with cataract extraction, the retention rate was 70% for 1 year and 62% for 2 years. Preoperative mean IOP was 21.6 ± 8.6 mm Hg; the number of glaucoma medications was 3.1 ± 1.1. At 24 months postoperatively, mean IOP was reduced 29% to 15.3 ± 4.6 mm Hg (P < 0.001) and the number of glaucoma medications was reduced 38% to 1.9 ± 1.3 (P < 0.001) with a success rate of 62% (95% CI, 56%-68%) using Criteria A and 22% (95% CI, 16%-29%) using Criteria B. Failure risk factors using C...Continue Reading

References

Nov 16, 2001·Journal of Cataract and Refractive Surgery·K HayashiF Hayashi
Jul 11, 2003·Progress in Retinal and Eye Research·Robert RitchAnastasios G P Konstas
Oct 1, 1958·A.M.A. Archives of Ophthalmology·W M GRANT
Aug 1, 1955·A.M.A. Archives of Ophthalmology·W M GRANT
Apr 7, 2005·Journal of Cataract and Refractive Surgery·Nurit MathaloneOrna Geyer
Jan 3, 2006·Experimental Eye Research·Mark Johnson
Jun 24, 2008·Journal of Cataract and Refractive Surgery·Brian A FrancisTrabectome Study Group
Dec 31, 2008·Experimental Eye Research·Ozan-Yüksel Tektas, Elke Lütjen-Drecoll
Jan 7, 2009·International Ophthalmology Clinics·Shashidhar Murthy, Mark A Latina
Jan 7, 2010·Journal of Glaucoma·Robert M Knape, Mary Fran Smith
Oct 11, 2011·Ophthalmology·Seung Youn JeaDouglas J Rhee
Feb 11, 2012·Journal of Cataract and Refractive Surgery·Jessica L M TingTrabectome Study Group
May 23, 2012·Ophthalmology·Steven L MansbergerOcular Hypertension Treatment Study Group
Jul 14, 2012·American Journal of Ophthalmology·Yachna AhujaArthur J Sit

Citations

Sep 13, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Randolf A WidderThomas S Dietlein
Feb 10, 2016·International Ophthalmology·Yildiray YildirimMelih Hamdi Unal
Jun 3, 2014·American Journal of Ophthalmology·Yachna AhujaArthur J Sit
Jan 21, 2014·American Journal of Ophthalmology·Arthur J Sit
Oct 4, 2015·Journal of Cataract and Refractive Surgery·Michelle KhanIqbal Ike K Ahmed
Aug 20, 2015·Journal of Cataract and Refractive Surgery·Jonathan Myers
Mar 1, 2016·Japanese Journal of Ophthalmology·Nobuyuki ShojiKimiya Shimizu
Jan 7, 2016·The British Journal of Ophthalmology·Kevin KaplowitzNils A Loewen
May 11, 2016·Survey of Ophthalmology·Julia K Polat, Nils A Loewen
Jan 26, 2016·PloS One·Sindhu SaraswathyAlex S Huang
Jul 7, 2018·Journal of Glaucoma·Lauriane SalinasKaweh Mansouri
Nov 6, 2018·Journal of Glaucoma·Masayuki KasaharaKazuhiro Matsumura
Jan 29, 2019·BMJ Open Ophthalmology·Swaantje GrisantiTsontcho Ianchulev
Jan 7, 2014·Current Opinion in Ophthalmology·Donald L Budenz, Steven J Gedde
Jun 13, 2018·Journal of Cataract and Refractive Surgery·Sasan MoghimiRobert N Weinreb
Aug 18, 2017·Journal of Glaucoma·Naoki TojoAtsushi Hayashi
Jan 7, 2018·Japanese Journal of Ophthalmology·Eri Kinoshita-NakanoTadamichi Akagi
Jun 15, 2017·Medicine·Constance O OkekeTrabectome Study Group
Aug 29, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yusuke KonoNobuyuki Shoji
Feb 11, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Markus AvarThomas Wecker
Jan 5, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Naoki Tojo, Atsushi Hayashi
Jan 1, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Milena PahlitzschEckart Bertelmann
Apr 11, 2018·Military Medicine·Brett L SmithWon I Kim
Jan 1, 2017·Expert Review of Ophthalmology·Emily M SchehleinOsamah J Saeedi
Sep 28, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hamed EsfandiariNils A Loewen
Jul 14, 2020·Journal of Cataract and Refractive Surgery·Steven R Sarkisian For The Ascrs Glaucoma Clinical Committee
Nov 6, 2020·Japanese Journal of Ophthalmology·Masayuki Kasahara, Nobuyuki Shoji

Related Concepts

Antihypertensive Agents
Phakectomy
Glaucoma, Open-Angle
Physiologic Intraocular Pressure
Retrospective Studies
Trabeculotomy
Cox Proportional Hazards Models
Cataract Extraction
Glaucoma
Mercury

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