Clinical safety of an MRI conditional implantable cardioverter defibrillator system: A prospective Monocenter ICD-Magnetic resonance Imaging feasibility study (MIMI)

Journal of Magnetic Resonance Imaging : JMRI
Alexander KyptaClemens Steinwender

Abstract

The aim of this study was to evaluate the safety and efficacy of the Lumax 740(®) Implantable Cardioverter Defibrillator (ICD) system in patients undergoing a defined 1.5 Tesla (T) MRI. Between November 2013 and April 2014, eighteen patients (age range, 41-78 years; mean age, 64 years) implanted with a Lumax 740(®) ICD system for at least 6 weeks before an MRI were enrolled into this single-center feasibility study. The local ethics committee approved the study before patients gave written informed consent. Patients underwent defined MRI 1.5T of the brain and lower lumbar spine with three safety follow-up evaluations obtained during the 3-month study period. Data were analyzed descriptively. Study endpoints were the absence of either MRI and pacing system related serious adverse device effects (SADE), or of a ventricular pacing threshold increase >0.5V, or of an R-wave amplitude attenuation < 50%, or of an R-wave amplitude < 5.0 mV at 1-month follow-up. The assessment of safety and efficacy was supported by recording of all adverse events, changes in pacing threshold, R-wave sensing, pacing impedances and in battery status. Sixteen patients completed the MRI and the follow-up period. As no SADE occurred, the SADE free rate was ...Continue Reading

References

Feb 15, 1986·The American Journal of Cardiology·J A ErlebacherR J Knowles
Jul 1, 1984·Pacing and Clinical Electrophysiology : PACE·J FetterD L Hayes
Apr 6, 2004·Journal of the American College of Cardiology·Edward T MartinKim Jenkins
Apr 14, 2005·Pacing and Clinical Electrophysiology : PACE·Ron Kalin, Marshall S Stanton
Mar 1, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ariel RoguinTorsten Sommer
Oct 12, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Bruce L WilkoffUNKNOWN EnRhythm MRI SureScan Pacing System Study Investigators
Sep 27, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Christian G WollmannHarald Mayr
Feb 15, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·William M BaileyUNKNOWN ProMRI/ProMRI AFFIRM Study Investigators

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Citations

Apr 4, 2018·Topics in Magnetic Resonance Imaging : TMRI·John P LichtenbergerBrett W Carter
Sep 27, 2018·Radiology·Rahul G MuthalalyArthur Nasis
Jul 10, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hermann BlessbergerJuergen Kammler
Nov 9, 2016·Korean Circulation Journal·You Mi HwangYou-Ho Kim
Jul 6, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Daniel KiblboeckClemens Steinwender

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