Clinical significance and management of subsegmental pulmonary embolism

Journal of Thrombosis and Thrombolysis
R Ikesaka, M Carrier

Abstract

Computed tomographic pulmonary angiography (CTPA) has a high sensitivity for diagnosing filling defects in subsegmental pulmonary arteries. The adoption of CTPA as the preferred diagnostic modality for the diagnosis of pulmonary embolism (PE) has led to an increased rate of PE diagnosis. However, the case fatality rate is lower and the mortality rate of PE has remained unchanged despite this rise in PE diagnosis suggesting that the disease is of lesser severity. There continues to be clinical equipoise on whether patients diagnosed with isolated subsegmental PE (SSPE) require anticoagulation or can be managed conservatively if the presence of deep vein thrombosis (DVT) has been excluded. Recent recommendations from the European Society of Cardiology suggest an individualized approach for the management of patients with newly diagnosed SSPE based on the risk/benefit ratio of anticoagulation and the presence of lower limb DVT. Prospective data evaluating the safety and efficacy of management strategies for SSPE is needed in order to determine the optimal management of these patients.

References

Jan 1, 1975·Progress in Cardiovascular Diseases·J E Dalen, J S Alpert
Apr 18, 1986·JAMA : the Journal of the American Medical Association·S E Dismuke, E H Wagner
Apr 2, 1994·BMJ : British Medical Journal·M NordströmT Kjellström
Jan 29, 1999·Lancet·A PerrierH Bounameaux
Jul 27, 2004·Journal of Thoracic Imaging·Conrad WittramJames H Thrall
Mar 1, 2005·Radiology·Lawrence R Goodman
Jun 2, 2006·The New England Journal of Medicine·Paul D SteinUNKNOWN PIOPED II Investigators
Jul 11, 2007·Archives of Internal Medicine·Diane K WysowskiLynette Swartz
Jul 1, 2008·The American Journal of Medicine·Nicholas A DeMonacoMargaret V Ragni
May 27, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Gregory W Gladish, Jeremy J Erasmus
Aug 21, 2010·Chest·Pierre-Yves SalaunGrégoire Le Gal
Feb 9, 2011·Thrombosis and Haemostasis·R PesaventoUNKNOWN TACEP study
Sep 29, 2011·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Paul D SteinFadi Matta
Jun 8, 2012·Journal of Thrombosis and Haemostasis : JTH·M CarrierG Le Gal
Sep 11, 2012·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Atul B ShinagareMizuki Nishino
Aug 21, 2013·Blood·Gary E Raskob
Sep 3, 2014·European Heart Journal·Stavros Konstantinides, Adam Torbicki
Oct 19, 2014·Journal of Thrombosis and Thrombolysis·Wang Yng LimAnthony Maraveyas

❮ Previous
Next ❯

Citations

Dec 26, 2015·Thrombosis Research·Soheil PeimanEnayat Safavi
Aug 25, 2016·Journal of the American Geriatrics Society·Stacy A JohnsonMatthew T Rondina
Nov 22, 2016·Expert Review of Hematology·Marc Carrier, Paolo Prandoni
Dec 23, 2016·AJR. American Journal of Roentgenology·Victor Chiu, Casey O'Connell
Aug 19, 2016·Postgraduate Medical Journal·Stephen Ellis, Zelena Aziz
Jun 9, 2016·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Prajwal DhakalVijaya R Bhatt
Jan 4, 2018·Ci Ji Yi Xue Za Zhi = Tzu-chi Medical Journal·I-Wen ChenKuo-Chuan Hung
May 31, 2018·Nuclear Medicine Communications·Amy MallorieThomas Wagner
Jan 10, 2020·Blood·Cecilia Becattini, Giancarlo Agnelli
Dec 24, 2016·Current Opinion in Pulmonary Medicine·Lauran StögerBram H J Geurts
Apr 12, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Gabriela LeuschnerNikolaus Kneidinger
Nov 30, 2019·European Heart Journal Supplements : Journal of the European Society of Cardiology·Luca ValerioStefano Barco
May 16, 2018·The Western Journal of Emergency Medicine·Murtaza AkhterChristopher Kabrhel
Aug 15, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Marika BajcBjorn Jonson
Dec 4, 2016·Hematology·Cecilia Becattini, Giancarlo Agnelli
Jun 29, 2017·Biomechanics and Modeling in Mechanobiology·Kenneth I AycockBrent A Craven
Jul 31, 2019·Physics in Medicine and Biology·Maria HolstenssonRimma Axelsson
Feb 5, 2021·Research and Practice in Thrombosis and Haemostasis·Christine Baumgartner, Tobias Tritschler
Feb 5, 2021·Research and Practice in Thrombosis and Haemostasis·Carmen Fernández-CapitánUNKNOWN RIETE Investigators
Mar 31, 2021·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Elsie T NguyenCarole Dennie
Aug 18, 2021·Thrombosis Research·Shannon M FernandoDaniel Brodie

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Thrombosis and Haemostasis : JTH
M CarrierG LE Gal
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
T YamakiT Kono
Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Gajan SivananthanJoseph F Polak
© 2021 Meta ULC. All rights reserved