Clinical significance and outcome of gastric mucosal erosions: a long-term follow-up study.

Digestive Diseases and Sciences
K T ToljamoJ K Lehtola

Abstract

Our purpose was to evaluate the long-term clinical significance of gastric erosions. A series of 117 patients with gastric erosions without peptic ulcer disease, and matched controls were studied in 1974-1979. All available subjects were reinvestigated 17 years later, including detailed clinical history and laboratory analysis. At follow-up, erosions were still more prevalent (39%; 20/50) in the erosion group than in the controls (11; 7/66). In Helicobacter pylori-positive participants, peptic ulcer or a scar was more common in the erosion group (17%; 9/52) than in controls (5%; 3/66). Overall malignancy rate was higher in controls (15%; 17/117) than in erosion group (5%; 6/117; P = .025), but no other differences were seen between the groups or related with current erosion. We conclude that a significant proportion of gastric erosions are chronic or recurrent but mostly without serious complications. However, H. pylori-positive patients with erosions have significant risk to develop a peptic ulcer.

References

Feb 1, 1979·Endoscopy·J FreiseH Huchzermeyer
Apr 1, 1988·Digestive Diseases and Sciences·L Laine, W M Weinstein
May 1, 1981·Gastrointestinal Endoscopy·F E SilversteinJ Persing
Dec 13, 2005·Scandinavian Journal of Gastroenterology·Kari T ToljamoTuomo J Karttunen

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Citations

Apr 3, 2012·World Journal of Gastroenterology : WJG·Ingrid Lisanne Holster, Ernst Johan Kuipers
Dec 3, 2014·Gastroenterology Clinics of North America·Eric T T L TjwaErnst J Kuipers
Jun 13, 2012·Digestive Diseases and Sciences·Sanjiv Mahadeva, Khean-Lee Goh
Mar 11, 2010·Journal of Clinical Biochemistry and Nutrition·Hiroyuki IshiiShigeru Kohno
Feb 5, 2011·Scandinavian Journal of Gastroenterology·Ritva Maria KoskelaTuomo Juhani Karttunen
Jul 9, 2008·Scandinavian Journal of Gastroenterology·Aino OksanenHilpi Rautelin

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