Clinical significance of extrapancreatic lesions in autoimmune pancreatitis

Pancreas
Itaru NaitohTakashi Joh

Abstract

To clarify the frequency and clinical significance of extrapancreatic lesions in autoimmune pancreatitis (AIP). The frequency and clinical characteristics of extrapancreatic lesions during the clinical course of AIP were investigated retrospectively in 64 patients with AIP. The predictive factors for relapse of AIP at clinical onset were also examined. Extrapancreatic lesions occurred in 95% (61/64) during the clinical course of AIP. The frequencies of sclerosing cholangitis, sclerosing sialadenitis, retroperitoneal fibrosis, and mediastinal or hilar lymphadenopathy were 84% (54/64), 23% (15/64), 16% (10/64), and 77% (27/35), respectively. Patients with sclerosing sialadenitis or extrapancreatic bile duct sclerosing cholangitis had a significantly higher serum immunoglobulin G concentration than those without (P = 0.005 and P = 0.016, respectively). Univariate analysis revealed that sclerosing sialadenitis (P = 0.005), diffuse pancreatic ductal changes (P = 0.028), and a high serum immunoglobulin G concentration (P = 0.030) at clinical onset of AIP were significant predictive factors for relapse. Multivariate analysis revealed that diffuse pancreatic ductal changes (P = 0.005) and sclerosing sialadenitis (P = 0.012) were signif...Continue Reading

References

Mar 10, 2001·The New England Journal of Medicine·Hideaki HamanoKendo Kiyosawa
Nov 14, 2003·Journal of Gastroenterology·Terumi KamisawaH Nakajima
Sep 28, 2005·Medicina clínica·Jorge MendozaJavier Pérez Gisbert
Oct 7, 2005·Journal of Clinical Gastroenterology·Terumi KamisawaAtsutake Okamoto
Dec 6, 2005·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Terumi KamisawaAtsutake Okamoto
Dec 13, 2005·Pancreas·Takashi MurakiKendo Kiyosawa
Jan 24, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kenji HiranoMasao Omata
May 12, 2006·World Journal of Gastroenterology : WJG·Kyu-Pyo KimSung-Koo Lee
Jul 18, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Suresh T ChariMichael B Farnell
Aug 26, 2006·Journal of Gastroenterology·Kazuichi OkazakiResearch Committee of Intractable Diseases of the Pancreas
Sep 19, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Lizhi ZhangThomas C Smyrk
Feb 9, 2007·Journal of Gastroenterology·Hideaki HamanoShigeyuki Kawa
May 9, 2007·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Elizabeth M Brunt
Dec 7, 2007·Gastrointestinal Endoscopy·Kensuke KubotaAtushi Nakajima
Oct 22, 2008·European Journal of Gastroenterology & Hepatology·Terumi KamisawaAtsutake Okamoto

Citations

Feb 22, 2012·Current Gastroenterology Reports·Raghuwansh P Sah, Suresh T Chari
Nov 5, 2010·World Journal of Gastroenterology : WJG·Kenji HiranoKazuhiko Koike
Jun 13, 2012·World Journal of Gastroenterology : WJG·Viktória TerzinLászló Czakó
Nov 28, 2013·World Journal of Gastroenterology : WJG·Takahiro NakazawaTakashi Joh
Mar 19, 2014·Journal of Gastroenterology·Terumi KamisawaWorking Committee of the Japan Pancreas Society and the Research Committee for Intractable Pancreatic Disease supported by t
Jun 2, 2012·International Journal of Rheumatology·Tobias PeikertEunhee S Yi
Sep 16, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Paraskevi A VlachouTae Kyoung Kim
Jan 17, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sree Harsha TirumaniChristine O Menias
Sep 29, 2011·Journal of Gastroenterology·Takahiro NakazawaTakashi Joh
Sep 29, 2011·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Jong Jin YooYun Jong Lee
Dec 3, 2010·Current Opinion in Rheumatology·Raghuwansh P Sah, Suresh T Chari
Apr 26, 2011·Journal of Thoracic Imaging·Katherine E MaturenRichard D Swartz
Feb 22, 2013·Journal of Clinical Gastroenterology·Sang Hyoung ParkJin-Ho Kim
Dec 3, 2015·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Itaru NaitohTakashi Joh
Dec 3, 2013·Current Problems in Diagnostic Radiology·Sushilkumar K Sonavane, Christine O Menias
Mar 24, 2015·Gastroenterología y hepatología·Carla Senosiain Lalastra, José Ramón Foruny Olcina
Sep 4, 2010·Journal of Hepato-biliary-pancreatic Sciences·Takahiro NakazawaTakashi Joh
Apr 17, 2012·Journal of Digestive Diseases·Hisato IgarashiRyoichi Takayanagi
Jun 22, 2012·Journal of Hepato-biliary-pancreatic Sciences·Hirotaka OharaJapan Biliary Association
Apr 30, 2013·Journal of Gastroenterology and Hepatology·Hirotaka OharaKazuichi Okazaki
Aug 20, 2014·Endocrinology, Diabetes & Metabolism Case Reports·Mahmud Abo SalookAmit Tirosh
Jul 18, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Takaaki OgoshiHiroshi Mukae
Aug 16, 2016·Clinics in Chest Medicine·Jay H Ryu, Eunhee S Yi
Jul 26, 2011·AJR. American Journal of Roentgenology·Alampady Krishna Prasad ShanbhogueMatthew McInnes
Dec 23, 2018·Journal of Hepato-biliary-pancreatic Sciences·Terumi KamisawaMasahiro Yoshida
Feb 20, 2019·Journal of Clinical Medicine·Miroslav VujasinovicJ-Matthias Löhr
Sep 8, 2019·Abdominal Radiology·Camila Lopes VendramiFrank H Miller
Mar 16, 2012·Scandinavian Journal of Gastroenterology·Itaru NaitohTakashi Joh

Related Concepts

Autoimmune Diseases
Polyglobin
Status Lymphaticus
Magnetization Transfer Contrast Imaging
Pancreatitis
Relapse
Retroperitoneal Fibrosis
Retrospective Studies
Irradiation-Induced Sialadenitis
Tomography, X-Ray Computerized Axial

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