PMID: 8945062Nov 1, 1996Paper

Clinical significance of increased OT dispersion in the 12-lead standard ECG for arrhythmia risk prediction in dilated cardiomyopathy

Pacing and Clinical Electrophysiology : PACE
W GrimmB Maisch

Abstract

QT dispersion was determined from the 12-lead standard ECGs from 107 patients with idiopathic dilated cardiomyopathy (IDG) and compared to QT dispersion measurements in 100 healthy age and sex matched controls. QT dispersion, rate corrected QT dispersion and adjusted QTc dispersion were significantly greater in patients with IDC compared to controls. During a prospective follow-up of 13 +/- 7 months, arrhythmic events, defined as sustained VT, VF, or sudden death, occurred in 12 (11%) of 107 study patients with IDC. QT dispersion was increased in patients with arrhythmic events compared to patients without arrhythmic events during follow-up (76 +/- 17 vs 60 +/- 26 ms; P = 0.03). Differences in QTc dispersion and adjusted QTc dispersion between patients with and without arrhythmic events, however, failed to reach statistical significance. Thus, although QT dispersion was increased in patients with IDC and arrhythmic events during follow-up, its clinical usefulness for risk stratification appears to be very limited due to the large overlap of QT dispersion among patients with and without arrhythmic events.

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Citations

Jul 20, 2001·International Journal of Cardiology·C CardosoA G Siqueira-Filho
Aug 10, 1999·Journal of the American College of Cardiology·K AdachiM Yokoyama
Apr 29, 2003·Pacing and Clinical Electrophysiology : PACE·Tatsuya KawasakiMasao Nakagawa
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Jan 10, 2012·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Zehra KarataşSevim Karaarslan
Feb 11, 2005·European Journal of Heart Failure·Laurent FauchierJean Paul Fauchier
Aug 3, 2004·Journal of Electrocardiology·Norikazu WatanabeTakashi Katagiri
May 4, 2002·The American Journal of Cardiology·Vladimir RankovicJeffrey J Goldberger
Oct 16, 2004·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Carlos Alberto PastoreJosé Antonio Franchini Ramires
Nov 14, 1997·Pacing and Clinical Electrophysiology : PACE·M A Murda'hA J Camm
Feb 2, 2021·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Saori KonnoShigetaka Shimodaira

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