Abstract
Mycobacterium avium complex (MAC) is frequently considered to be a contaminant or transient colonizer. To the best of our knowledge, there have been very few reports regarding the clinical significance of MAC isolates in respiratory specimens, and the associated disease spectrum in Taiwan. The purpose of this study was to investigate the clinical significance of MAC isolates in respiratory specimens. We retrospectively reviewed the medical records of patients in a medical center in Southern Taiwan from whom MAC isolates were recovered from respiratory specimens, and analyzed their clinical features, chest imaging findings, treatment and prognosis. We also performed an antibiotic susceptibility test on our MAC isolates. The 64 isolates used in this study were recovered from April to October 2001 from respiratory specimens in 54 patients admitted to Kaohsiung Veterans General Hospital, Taiwan. According to the 2007 criteria of the American Thoracic Society, a total of 12 patients (22.2%) had clinically significant MAC pulmonary disease. Despite the increased frequency of recovering MAC from respiratory specimens, most cases did not meet the criteria of American Thoracic Society for clinically significant nontuberculous pulmonary ...Continue Reading
References
Jul 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S ChoudhriR Long
Mar 1, 1996·Journal of Medical Microbiology·W FabryR Ansorg
Jun 1, 1997·American Journal of Respiratory and Critical Care Medicine·E TanakaF Kuze
Jul 23, 1998·Chest·A A El-SolhB J Grant
Oct 21, 1998·Lung·K KuboS Sone
Feb 17, 2001·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·B Raju, N W Schluger
Jul 31, 2001·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F RoosUNKNOWN Swiss HIV Cohort Study
Dec 2, 2005·The European Respiratory Journal·J MaugeinUNKNOWN French Mycobacteria Study Group
Feb 24, 2006·Epidemiology and Infection·L W DingP R Hsueh
Sep 1, 2006·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Yoshihiro KobashiMikio Oka
Sep 7, 2006·Respiration; International Review of Thoracic Diseases·Yoshihiro Kobashi, Toshiharu Matsushima
Feb 6, 2007·American Journal of Respiratory and Critical Care Medicine·David E GriffithUNKNOWN Infectious Disease Society of America
Jan 12, 2008·Chest·Jeffrey Glassroth
Jul 1, 2008·Expert Review of Anti-infective Therapy·Marcelo Corti, Domingo Palmero
Aug 16, 2008·Internal Medicine·Masao OkumuraShoji Kudoh
Sep 24, 2008·Seminars in Respiratory and Critical Care Medicine·Shannon H Kasperbauer, Charles L Daley