Clinical Significance of Lymphoscintigraphy Findings in the Evaluation of Lower Extremity Lymphedema

Molecular Imaging and Radionuclide Therapy
Seyhan KaraçavuşHasan Ekim

Abstract

The purpose of this study was to investigate the clinical significance of lymphoscintigraphy imaging in the evaluation of lower extremity lymphedema. Technetium-99m-labeled nanocolloid was injected subcutaneously in the first web spaces of both feet of 123 patients (M/F: 43/80, mean age 57.5±13.1 years, range 16-78 years) who had clinical evidence of lower extremity swelling with suspicion of lymphedema, and were referred for routine lymphoscintigraphy. Lymphoscintigraphy scan was started as dynamic viewing followed by static whole body imaging at 10 minute, 1 hour and 4 hours after injection. Eighty-seven patients had lymphedema. Patients who had lymphedema were divided into two groups according to their scintigraphy findings: Group I included 58 patients without uptake in the popliteal nodes, and group II included 29 patients with positive popliteal nodes. The rate of popliteal node visualization was higher in patients with dermal backflow as compared to those without dermal backflow (p<0.001). The duration of lymphedema was also longer in patients with dermal backflow and popliteal nodes (p<0.004). Lymphoscintigraphy is a reliable, easily applied and well-tolerated objective method to diagnose lower extremity lymphedema. Upt...Continue Reading

Citations

May 11, 2016·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C R LattimerG Geroulakos
May 22, 2013·Respiratory Medicine·Yoshito HoshikaKuniaki Seyama
Oct 3, 2013·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Betty SmootMarylin Dodd
Mar 26, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Shinsuke AkitaKaneshige Satoh
Sep 7, 2017·Annual Review of Medicine·Joseph H DayanBabak J Mehrara
Apr 18, 2021·The European Respiratory Journal·Victor E Maldonado-ZimbronAnthony Ronald John Phillips

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Methods Mentioned

BETA
imaging technique

Software Mentioned

SPSS
SPSS ( Statistical Package for the Social Science

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