Clinical significance of positive penicillin test reactions (author's transl)

Deutsche medizinische Wochenschrift
E G HanekeE Haneke

Abstract

Epicutaneous, scratch and intracutaneous tests with various penicillins and their major as well as minor determinants were performed on 495 patients either because they were suspected of having a penicillin allergy, or in order to exclude such allergy, or before starting penicillin treatment, or because they suffered from chronic recurrent urticaria. A positive test reaction occurred in 25%: 44% among those with a history pointing to penicillin allergy and 17.8% among those who were tested before treatment to exclude penicillin allergy. Positive reactions also occurred in 11% of patients with chronic recurrent urticaria, but in practically all instances were clinically without significance. D-Penicillamine (Metalcaptase) and penicilloyl-polysine in the intracutaneous test, penicillin-G-sodium and ampicillin in the epicutaneous test gave the highest incidence of positive reactions.

Citations

Jul 1, 1997·Clinics in Dermatology·D P Bruynzeel, H I Maibach
Nov 1, 1985·The British Journal of Dermatology·M C Heng

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