PMID: 11916160Mar 28, 2002Paper

Clinical significance of small polyps found during screening with flexible sigmoidoscopy

Gastrointestinal Endoscopy Clinics of North America
Francis A Farraye, Michael Wallace

Abstract

In deciding how to interpret the significance and management of small distal adenomatous polyps found on FS, one must first decide on the goal of a screening program. If the goal is maximal reduction of CRC risk, regardless of cost, there is little argument that screening colonoscopy is the most effective approach. Unfortunately cost and cost-effectiveness are important considerations when administering a screening program with a fixed budget. Although comparing the cost-effectiveness of different strategies is beyond the scope of this article, rigorous comparisons by other authors have suggested that a sigmoidoscopy-based approach is more cost-effective than a colonoscopy-based approach. The most cost-effective approach may change, however, if the frequency of screening and surveillance can be reduced without significantly impacting effectiveness. Other authors using assumptions including low compliance rates for regular FOBT or FS have determined that colonoscopy every 10 years is the most cost-effective approach. Multiple studies support the recommendation that villous polyps regardless of size and adenomatous polyps greater than 1 cm found on FS are important markers for the presence of advanced polyps and cancer in the pro...Continue Reading

References

Mar 1, 1978·Cancer·V A Gilbertsen, J M Nelms
Dec 1, 1988·Annals of Internal Medicine·E Achkar, W Carey

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Citations

May 4, 2005·Cancer Causes & Control : CCC·Christopher S HuangFrancis A Farraye
Sep 29, 2011·Journal of Clinical Psychology in Medical Settings·M LauriolaA E Potenza
Aug 2, 2003·Cancer Detection and Prevention·Kevin O'BrienKevin A Lang
Nov 23, 2006·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·J P Heiken
Apr 21, 2010·Current Oncology·P H Gordon
Nov 9, 2011·Journal of General Internal Medicine·Dimitra Dodou, Joost C F de Winter
Feb 6, 2007·American Journal of Clinical Pathology·Alexandros D Polydorides, Rhonda K Yantiss
Nov 13, 2007·Gastroenterology Clinics of North America·Michael J O'Brien
Nov 10, 2005·Gastrointestinal Endoscopy Clinics of North America·David BurlingSteve Halligan
Mar 22, 2006·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·R Anwar
Nov 24, 2004·The American Journal of Gastroenterology·Christopher S HuangFrancis A Farraye
Nov 19, 2003·European Journal of Gastroenterology & Hepatology·Teresa M GalloDaniele Regge
Jul 3, 2003·JAMA : the Journal of the American Medical Association·Robert H Fletcher

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